[HTML][HTML] Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion

N Rodman, J Martinez, S Fung, J Nakanouchi… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii (Ab) is one of the most treacherous pathogens among those
causing hospital-acquired pneumonia (HAP). A. baumannii possesses an adaptable …

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

MS Bhuiyan, F Ellett, GL Murray… - Proceedings of the …, 2016 - National Acad Sciences
Innate cellular immune responses are a critical first-line defense against invading bacterial
pathogens. Leukocyte migration from the bloodstream to a site of infection is mediated by …

[HTML][HTML] Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress

J Martinez, JS Fernandez, C Liu, A Hoard… - Scientific reports, 2019 - nature.com
Acinetobacter baumannii is a feared, drug-resistant pathogen, characterized by its ability to
resist extreme environmental and nutrient-deprived conditions. Previously, we showed that …

[HTML][HTML] Human Pleural Fluid and Human Serum Albumin Modulate the Behavior of a Hypervirulent and Multidrug-Resistant (MDR) Acinetobacter baumannii …

C Pimentel, C Le, MR Tuttobene, T Subils, J Martinez… - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is a nosocomial pathogen capable of causing serious infections
associated with high rates of morbidity and mortality. Due to its antimicrobial drug resistance …

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia

GL Murray, K Tsyganov, XP Kostoulias… - The Journal of …, 2017 - academic.oup.com
Background. Acinetobacter baumannii is a pathogen of major importance in intensive care
units worldwide, with the potential to cause problematic outbreaks and acquire high-level …

[HTML][HTML] Transcriptome Profiling of Lung Innate Immune Responses Potentially Associated With the Pathogenesis of Acinetobacter baumannii Acute Lethal …

X Zeng, H Gu, L Peng, Y Yang, N Wang, Y Shi… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is one of the dominating causes of nosocomial pneumonia,
however, very little is known about the host immune response associated with pathogenesis …

[HTML][HTML] Deciphering the virulence factors, regulation, and immune response to Acinetobacter baumannii infection

A Shadan, A Pathak, Y Ma, R Pathania… - Frontiers in Cellular and …, 2023 - frontiersin.org
Deciphering the virulence factors, regulation, and immune response to Acinetobacter
baumannii infection Acinetobacter baumannii is a gram-negative multidrug-resistant …

Characterization of the Acinetobacter baumannii growth phase-dependent and serum responsive transcriptomes

AC Jacobs, K Sayood, SB Olmsted… - FEMS Immunology & …, 2012 - academic.oup.com
Acinetobacter baumannii has emerged as a bacterial pathogen of considerable healthcare
concern. Yet, little is known about the organism's basic biological processes and the …

[HTML][HTML] Genome-Scale Metabolic Modeling Reveals Metabolic Alterations of Multidrug-Resistant Acinetobacter baumannii in a Murine Bloodstream Infection Model

J Zhao, Y Zhu, J Han, YW Lin, M Aichem, J Wang… - Microorganisms, 2020 - mdpi.com
Multidrug-resistant (MDR) Acinetobacter baumannii is a critical threat to human health
globally. We constructed a genome-scale metabolic model i AB5075 for the hypervirulent …

Interactions between host epithelial cells and Acinetobacter baumannii promote the emergence of highly antibiotic resistant and highly mucoid strains

W Zhang, Y Yao, H Zhou, J He, J Wang… - Emerging microbes & …, 2022 - Taylor & Francis
Acinetobacter baumannii is an important nosocomial pathogen. Upon colonizing a host, A.
baumannii are subjected to selective pressure by immune defenses as they adapt to the …