[HTML][HTML] Hepatoprotective, antioxidant, anti-inflammatory, and antiviral activities of silymarin against mayaro virus infection

AC Ferraz, LT Almeida, CC da Silva Caetano… - Antiviral Research, 2021 - Elsevier
Infection caused by Mayaro virus (MAYV) is responsible for causing acute nonspecific fever,
in which the majority of patients develop incapacitating and persistent arthritis/arthralgia …

Antiviral activity of silymarin against Mayaro virus and protective effect in virus-induced oxidative stress

FC Camini, TF da Silva, CC da Silva Caetano… - Antiviral research, 2018 - Elsevier
Mayaro virus (MAYV) is a neglected arbovirus belonging to the family Togaviridae. Its
infection leads to Mayaro fever, with clinical manifestations such as fever, myalgia …

Mayaro virus induction of oxidative stress is associated with liver pathology in a non-lethal mouse model

CC da Silva Caetano, FC Camini, LT Almeida… - Scientific reports, 2019 - nature.com
Mayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with
persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic …

[HTML][HTML] Oxidative stress in Mayaro virus infection

FC Camini, CC da Silva Caetano, LT Almeida… - Virus research, 2017 - Elsevier
Mayaro virus (MAYV) is a neglected tropical arbovirus that causes a febrile syndrome that is
sometimes accompanied by incapacitating arthritis/arthralgia. The pathogenesis of MAYV …

Mayaro virus infection elicits a robust pro-inflammatory and antiviral response in human macrophages

LJ Hernández-Sarmiento, YS Tamayo-Molina… - Acta Tropica, 2024 - Elsevier
Mayaro virus (MAYV), the etiological agent of Mayaro fever (MAYF), is an emergent
arbovirus pathogen belonging to Togaviridae family. MAYF is characterized by high …

Inhibition of p38 mitogen-activated protein kinase impairs mayaro virus replication in human dermal fibroblasts and HeLa cells

M Sugasti-Salazar, YY Llamas-González, D Campos… - Viruses, 2021 - mdpi.com
Mayaro virus (MAYV) hijacks the host's cell machinery to effectively replicate. The mitogen-
activated protein kinases (MAPKs) p38, JNK, and ERK1/2 have emerged as crucial cellular …

Mayaro virus: The state-of-the-art for antiviral drug development

AP Andreolla, AA Borges, J Bordignon… - Viruses, 2022 - mdpi.com
Mayaro virus is an emerging arbovirus that causes nonspecific febrile illness or arthralgia
syndromes similar to the Chikungunya virus, a virus closely related from the Togaviridae …

Mayaro virus replication restriction and induction of muscular inflammation in mice are dependent on age, type-I interferon response, and adaptive immunity

CM Figueiredo, RLS Neris… - Frontiers in …, 2019 - frontiersin.org
Mayaro virus (MAYV) is an emergent arbovirus first described in forest regions of the
American continent, with recent and increasing notification of urban area circulation. Similar …

[HTML][HTML] Macrophages as target cells for Mayaro virus infection: involvement of reactive oxygen species in the inflammatory response during virus replication

MG Cavalheiro, LS Costa, HS Campos… - Anais da Academia …, 2016 - SciELO Brasil
Alphaviruses among the viruses that cause arthritis, consisting in a public health problem
worldwide by causing localized outbreaks, as well as large epidemics in humans …

Long-term arthralgia after Mayaro virus infection correlates with sustained pro-inflammatory cytokine response

FW Santiago, ES Halsey, C Siles… - PLoS neglected …, 2015 - journals.plos.org
Mayaro virus (MAYV), an alphavirus similar to chikungunya virus (CHIKV), causes an acute
debilitating disease which results in the development of long-term arthralgia in more than …