Key points Both brown adipose tissue (BAT) and skeletal muscle activation contribute to the
metabolic response of acute cold exposure in healthy men even under minimal shivering …

Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists
of a combination of cold‐induced increases in skeletal muscle proton leak and shivering …

Context: Recent studies examining brown adipose tissue (BAT) metabolism in adult humans
have provided convincing evidence of its thermogenic potential and role in clearing …

The relative roles of circulatory glucose, muscle glycogen, and lipids in shivering
thermogenesis are unclear. Using a combination of indirect calorimetry and stable isotope …

Recruitment of brown adipose tissue (BAT) has emerged as a potential tool to combat
obesity and associated metabolic complications. Short-term cold acclimation has been …

Brown adipose tissue (BAT) contributes to whole body energy expenditure (EE), especially
cold-induced thermogenesis (CIT), in humans. Although it is known that EE and CIT vary …

To maintain core body temperature in cold conditions, mammals activate a complex multi-
organ metabolic response for heat production. White adipose tissue (WAT) primarily …

Human studies suggest that a meal elevates glucose uptake in brown adipose tissue (BAT).
However, in postprandial state the thermogenic activity and the metabolism of non-esterified …

Indirect evidence from human studies suggests that brown adipose tissue (BAT)
thermogenesis is fueled predominantly by fatty acids hydrolyzed from intracellular …

Context: The contribution of brown adipose tissue (BAT) to the energy balance in humans
exposed to sustainable cold has not been completely established, partially because of …