Transcription factors (TFs) preferentially bind sites contained in regions of computationally
predicted high nucleosomal occupancy, suggesting that nucleosomes are gatekeepers of TF …

Active eukaryotic regulatory sites are characterized by open chromatin, and yeast promoters
and transcription factor binding sites (TFBSs) typically have low intrinsic nucleosome …

Gene expression is controlled by sequence-specific transcription factors (TFs), which bind to
regulatory sequences in DNA. TF binding occurs in nucleosome-depleted regions of DNA …

Transcription factors (TFs) selectively bind distinct sets of sites in different cell types. Such
cell type-specific binding specificity is expected to result from interplay between the TF's …

It is currently not possible to resolve the genome-wide relationship of transcription factors
(TFs) and nucleosomes at the level of individual chromatin templates despite rapidly …

Gene regulatory programs in distinct cell types are maintained in large part through the cell-
type–specific binding of transcription factors (TFs). The determinants of TF binding include …

Precise gene expression patterns are established by transcription factor (TFs) binding to
regulatory sequences. While these events occur in the context of chromatin, our …

Enhancers harbor binding motifs that recruit transcription factors (TFs) for gene activation.
While cooperative binding of TFs at enhancers is known to be critical for transcriptional …

Fate-changing transcription factors (TFs) scan chromatin to initiate new genetic programs
during cell differentiation and reprogramming. Yet the protein structure domains that allow …

Chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) has
become the dominant technique for mapping transcription factor (TF) binding regions …