Osteoarthritis (OA) is progressive disease characterised by cartilage degradation,
subchondral bone remodelling and inflammation of the synovium. The disease is associated …

The aim of this review is to provide an updated review of the epigenetic factors involved in
the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint …

The field of genetics and genomics is a highly technological driven field that is advancing
fast. The purpose of this year in review of genetics and genomics was to highlight the …

Osteoarthritis (OA) is the most common type of arthritis and no longer is considered as an
absolute consequence of joint mechanical use (wear and tear); rather recent data …

Genetic studies have revealed that most loci associated with osteoarthritis (OA) show ethnic
stratification, with limited overlap between Asian and European populations. Consequently …

Recent developments in genetics/genomics of osteoarthritis (OA) are discussed to improve
our understanding of OA pathophysiology. The discovery of a novel variant near the NCOA3 …

Osteoarthritis (OA) is the most common form of joint disease and the leading cause of
chronic disability in middle-aged and older populations. The development of disease …

Recent genome-wide association scans (GWASs) along with several adequately powered
candidate gene studies have yielded a number of risk alleles for osteoarthritis (OA). This …

Osteoarthritis represents the most frequently diagnosed condition of the musculoskeletal
system and accounts for a high amount of direct and indirect socioeconomic costs …

Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by
mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary …