A novel, cheap and easy-to-construct device and a simple method for partition coefficient
determination in liposome/water system based on modified equilibrium dialysis have been …

Purpose. To investigate a novel approach for the determination of liposomal membrane-
water partition coefficients and lipophilicity profiles of ionizable drugs. Methods. The …

Apparent partition coefficients (D) of (RS)-[3H] propranolol, 14C-lidocaine, 14C-diazepam,
14C-warfarin, 14C-salicylic acid and 14C-cyclosporine A were determined in a …

Purpose. To study the partitioning of model acids ((RS)-warfarin and salicylic acid), and
bases (lidocaine,(RS)-propranolol and diazepam), with immobilized artificial membrane …

The Grunbauer's method using multiple-regression analysis has been applied to determine
the partition coefficients in liposome/water systems after a modification to an ideal case …

An electrochemical method for the determination of the liposome–water partition coefficients
of drugs was developed. Interactions of liposomes and β-blockers were studied using …

Drug partitioning to liposomes has been suggested as a model for partitioning to
biomembranes but has been lacking a rapid analytical assay useful for drug screening. A …

The experimental determination of liposome− water partition coefficients, K lipw, of the
neutral and charged species of ionogenic compounds is rather tedious because apparent …

A chromatographic method for the determination of association constants of rapidly
dissociable complexes is descibed and applied to quantification of liposome/saline partition …

A method for the evaluation of liposome size populations using sucrose density gradient
centrifugation coupled with a continuous flow system is presented. Liposomes, prepared …