Pulmonary niche dynamically orchestrates the signals, such as proliferation or differentiation
of mesenchymal stem cells (MSCs), which allows inducing tissue repair. Lung niche …

Hyaluronic acid (HA) is an essential component of the extracellular matrix (ECM) of the
healthy lung, playing an important role in the structure of the alveolar surface stabilizing the …

Pharmacological therapies in lung diseases are nowadays useful in reducing the
symptomatology of lung injury. However, they have not yet been translated to effective …

Background Mesenchymal stem cells (MSC) are in clinical trials for widespread indications
including musculoskeletal, neurological, cardiac and haematological disorders …

Identification of appropriate donor cell types is important for lung cell therapy and for lung
regeneration. Previous studies have indicated that mesenchymal stromal cells derived from …

Abstract Purpose Mesenchymal stem cells (MSCs) represent a promising source for stem
cell therapies in numerous diseases, including pediatric respiratory system diseases …

Mesenchymal stromal cell (MSC)-based therapies for inflammatory diseases rely mainly on
the paracrine ability to modulate the activity of macrophages. Despite recent advances, there …

It is known that the cell environment such as biomechanical properties and extracellular
matrix (ECM) composition dictate cell behaviour including migration, proliferation, and …

Mesenchymal stromal cell (MSC)-based cell therapy in acute respiratory diseases is based
on MSC secretion of paracrine factors. Several strategies have proposed to improve this are …

Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …