AGA clinical practice update on de-prescribing of proton pump inhibitors: expert review

LE Targownik, DA Fisher, SD Saini - Gastroenterology, 2022 - Elsevier
Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Deprescribing proton pump inhibitors: evidence-based clinical practice guideline

B Farrell, K Pottie, W Thompson, T Boghossian… - Canadian Family …, 2017 - cfp.ca
Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper or stop proton pump inhibitors (PPIs); to focus on the highest …

The risks and benefits of long-term use of proton pump inhibitors: expert review and best practice advice from the American Gastroenterological Association

DE Freedberg, LS Kim, YX Yang - Gastroenterology, 2017 - Elsevier
Background & Aims The purpose of this review is to evaluate the risks associated with long-
term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three …

Potentially inappropriate proton-pump inhibitor prescription in the general population: a claims-based retrospective time trend analysis

L Muheim, A Signorell, S Markun… - Therapeutic …, 2021 - journals.sagepub.com
Background: Proton-pump inhibitors (PPI) are among the most prescribed drugs worldwide,
and a large body of evidence raises concerns about their inappropriate use. Previous …

The use and misuse of proton pump inhibitors: an opportunity for deprescribing

TS Dharmarajan - Journal of the American Medical Directors Association, 2021 - Elsevier
Proton pump inhibitors (PPIs) are proven medications of choice for gastroesophageal reflux
disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention …

Proton pump inhibitor utilisation and potentially inappropriate prescribing analysis: insights from a single-centred retrospective study

Y Liu, X Zhu, R Li, J Zhang, F Zhang - BMJ open, 2020 - bmjopen.bmj.com
Objectives This study aimed to characterise the prescribing patterns and evaluate the
appropriateness of the prescribed proton pump inhibitors (PPIs) in adult patients via a …

The inappropriate prescription of oral proton pump inhibitors in the hospital setting: a prospective cross-sectional study

OB Kelly, C Dillane, SE Patchett, GC Harewood… - Digestive diseases and …, 2015 - Springer
Proton pump inhibitors (PPIs) are used to treat upper gastrointestinal tract disorders. Their
efficacy and perceived safety have led to widespread prescription. This is not without effect …

Patients' perceptions of proton pump inhibitor risks and attempts at discontinuation: a national survey

JE Kurlander, JK Kennedy, JH Rubenstein… - Official journal of the …, 2019 - journals.lww.com
OBJECTIVES: Little is known about how reports on the adverse effects of proton pump
inhibitors (PPIs) impact patients' perceptions of these drugs and medication use. We sought …

Proton pump inhibitor use: systematic review of global trends and practices

LGT Shanika, A Reynolds, S Pattison… - European Journal of …, 2023 - Springer
Abstract Purpose Proton pump inhibitors (PPIs) reduce acid secretion in the stomach and
rank as one of the most widely used acid-suppressing medicines globally. While PPIs are …

Changes in proton pump inhibitor prescribing trend over the past decade and pharmacists' effect on prescribing practice at a tertiary hospital

H Luo, Q Fan, S Xiao, K Chen - BMC health services research, 2018 - Springer
Abstract Background Proton pump inhibitors (PPIs) remain one of the world's most frequently
prescribed medications and there is a growing number of publications on correct versus …