[HTML][HTML] Peroxisome proliferator-activated receptors and the hallmarks of cancer

N Wagner, KD Wagner - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

[HTML][HTML] PPAR beta/delta and the hallmarks of cancer

N Wagner, KD Wagner - Cells, 2020 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone
receptor family. Three different isoforms, PPAR alpha, PPAR beta/delta and PPAR gamma …

Peroxisome proliferator‐activated receptors and cancer: challenges and opportunities

J Youssef, M Badr - British journal of pharmacology, 2011 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs), members of the nuclear hormone
receptor superfamily, function as transcription factors and modulators of gene expression …

PPARγ as a therapeutic target for tumor angiogenesis and metastasis

D Panigraphy, S Huang, MW Kieran… - Cancer biology & …, 2005 - Taylor & Francis
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors with pleiotropic effects on cell fate and metabolism. Because of its anti-proliferative …

[HTML][HTML] PPARα ligands as antitumorigenic and antiangiogenic agents

A Pozzi, JH Capdevila - PPAR research, 2008 - ncbi.nlm.nih.gov
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor family of
ligand-activated transcription factors. This subfamily is composed of three members …

Peroxisome proliferator activated receptor-gamma ligands as potent antineoplastic agents

S Theocharis, A Margeli… - … Medicinal Chemistry-Anti …, 2003 - ingentaconnect.com
The Peroxisome Proliferator Activated Receptors (PPARs) are initially described as
molecular targets for compounds inducing peroxisome proliferation. Among the three PPAR …

Present concepts and future outlook: function of peroxisome proliferator‐activated receptors (PPARs) for pathogenesis, progression, and therapy of cancer

P Sertznig, M Seifert, W Tilgen… - Journal of cellular …, 2007 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs) are members of the nuclear receptor
superfamily of transcriptional regulators that regulate lipid, glucose, and amino acid …

Peroxisome-proliferator-activated receptors and cancers: complex stories

L Michalik, B Desvergne, W Wahli - Nature Reviews Cancer, 2004 - nature.com
Peroxisome-proliferator-activated receptors (PPARs) are nuclear hormone receptors that
mediate the effects of fatty acids and their derivatives at the transcriptional level. Through …

Peroxisome proliferator activated receptor-γ (PPAR-γ) ligands and angiogenesis

A Margeli, G Kouraklis, S Theocharis - Angiogenesis, 2003 - Springer
The peroxisome proliferator activated receptor (PPAR)-γ ligands have been initially
described as important regulators of adipogenic differentiation and glucose homeostasis …

PPARs and angiogenesis

D Bishop-Bailey - Biochemical Society Transactions, 2011 - portlandpress.com
The PPAR (peroxisome-proliferator-activated receptor) family consists of three ligand-
activated nuclear receptors: PPARα, PPARβ/δ and PPARγ. These PPARs have important …