Delayed diagnosis of narcolepsy: characterization and impact

MJ Thorpy, AC Krieger - Sleep medicine, 2014 - Elsevier
Narcolepsy, a chronic neurologic condition resulting from dysregulation of the sleep–wake
cycle, usually has an onset at an early age. However, a long delay until diagnosis has been …

Factors associated with a delay in the diagnosis of narcolepsy

E Morrish, MA King, IE Smith, JM Shneerson - Sleep medicine, 2004 - Elsevier
Background: There can be a long interval from the onset of symptoms before a diagnosis of
narcolepsy is made. There are no multivariate analyses reported in the literature of factors …

The humanistic and economic burden of narcolepsy

NM Flores, KF Villa, J Black, RD Chervin… - Journal of Clinical Sleep …, 2016 - jcsm.aasm.org
Study Objectives: To evaluate the burden of narcolepsy--with respect to psychiatric
comorbidities, Health-Related Quality of Life (HRQoL), direct costs for healthcare resource …

Delayed diagnosis, range of severity, and multiple sleep comorbidities: a clinical and polysomnographic analysis of 100 patients of the innsbruck narcolepsy cohort

B Frauscher, L Ehrmann, T Mitterling… - Journal of Clinical …, 2013 - jcsm.aasm.org
Study Objectives: Narcolepsy is reported to affect 26-56/100,000 in the general population.
We aimed to describe clinical and polysomnographic features of a large narcolepsy cohort …

Comorbidities in a community sample of narcolepsy

A Cohen, J Mandrekar, EKS Louis, MH Silber… - Sleep medicine, 2018 - Elsevier
Study objective To assess comorbidities in a community-based cohort of narcolepsy.
Methods A 2000–2014 community-based narcolepsy cohort was identified in Olmsted …

[HTML][HTML] Clinical characteristics and burden of illness in pediatric patients with narcolepsy

G Plazzi, HM Clawges, JA Owens - Pediatric Neurology, 2018 - Elsevier
Background: Narcolepsy is a chronic and lifelong neurologic disorder with onset commonly
occurring in childhood or adolescence, and affecting approximately 0.025% to 0.05% of the …

Current concepts in the etiology, diagnosis and treatment of narcolepsy

M Thorpy - Sleep medicine, 2001 - Elsevier
Background and purpose: Narcolepsy is the most common neurologic cause of excessive
daytime sleepiness. Rapid eye movement (REM) sleep phenomena such as cataplexy …

Idling for decades: A European study on risk factors associated with the delay before a narcolepsy diagnosis

Z Zhang, Y Dauvilliers, G Plazzi, G Mayer… - Nature and science of …, 2022 - Taylor & Francis
Purpose Narcolepsy type-1 (NT1) is a rare chronic neurological sleep disorder with
excessive daytime sleepiness (EDS) as usual first and cataplexy as pathognomonic …

Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population

MM Ohayon - Sleep medicine, 2013 - Elsevier
BACKGROUND: Individuals affected with narcolepsy represent a vulnerable segment of the
population. However, we only have a partial understanding of this vulnerability. Our study …

Disrupted nighttime sleep in narcolepsy

T Roth, Y Dauvilliers, E Mignot, J Montplaisir… - Journal of Clinical …, 2013 - jcsm.aasm.org
Study Objectives: Characterize disrupted nighttime sleep (DNS) in narcolepsy, an important
symptom of narcolepsy. Methods: A panel of international narcolepsy experts was convened …