Cystic fibrosis (CF), the second most common lifeshortening autosomal recessive genetic
disorder in the United States, is characterized by abnormal secretions in multiple organ …

The 21st century has witnessed dramatic advances in the care for people affected by cystic
fibrosis (CF). Known for decades as a frequently lethal disease during childhood, it is …

Cystic fibrosis (CF) arises from the mutation of a single gene encoding the cystic fibrosis
transmembrane conductance regulator (CFTR), 1 a chloride channel that is widely …

Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the
gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein …

Introduction Great variation exists in the progression and outcomes of cystic fibrosis (CF)
lung disease, due to both genetic and environmental influences. Social determinants …

Understanding variability in cystic fibrosis (CF) health outcomes requires an understanding
of factors that go far beyond Cystic Fibrosis Transmembrane Receptor (CFTR) function …

Extract Cystic fibrosis (CF) is one of the most common autosomal recessive genetic
conditions that causes progressive lung disease and premature death [1]. Median survival …

The clinical phenotype of cystic fibrosis (CF), chronic infection, and inflammation leading to
progressive obstructive lung disease and pancreatic insufficiency is caused by absence or …

Cystic fibrosis (CF) has seen a multitude of therapeutic advances targeting its downstream
effects. This has led to a steady increase in survival over the past few decades. The recent …

Cystic fibrosis (CF) is a common life-shortening autosomal recessive genetic disorder that is
characterized by eccrine (sweat) gland dysfunction, chronic obstructive lung disease, and …