Oxidative stress: a new target for pancreatic cancer prognosis and treatment

J Martinez-Useros, W Li, M Cabeza-Morales… - Journal of clinical …, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of tumors, and its
incidence is rising worldwide. Survival can be improved when tumors are detected at an …

[HTML][HTML] Oxidative stress and cytokines in the pathogenesis of pancreatic cancer

JH Yu, H Kim - Journal of cancer prevention, 2014 - ncbi.nlm.nih.gov
Pancreatic cancer is one of the most aggressive, drug-resistant and lethal types of cancer
with poor prognosis. Various factors including reactive oxygen species, cytokines, growth …

Reactive oxygen species and targeted therapy for pancreatic cancer

L Zhang, J Li, L Zong, X Chen, K Chen… - Oxidative medicine …, 2016 - Wiley Online Library
Pancreatic cancer is the fourth leading cause of cancer‐related death in the United States.
Reactive oxygen species (ROS) are generally increased in pancreatic cancer cells …

Targeting reactive oxygen species in development and progression of pancreatic cancer

N Durand, P Storz - Expert review of anticancer therapy, 2017 - Taylor & Francis
Introduction: Pancreatic ductal adenocarcinoma (PDA) is characterized by expression of
oncogenic KRas which drives all aspects of tumorigenesis. Oncogenic KRas induces the …

Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer

L Milkovic, W Siems, R Siems… - Current pharmaceutical …, 2014 - ingentaconnect.com
Oxidative stress is often considered as a causative factor in carcinogenesis. In addition,
current knowledge recognizes oxidative stress as a mechanism by which various cancer …

Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

New hope for pancreatic ductal adenocarcinoma treatment targeting endoplasmic reticulum stress response: a systematic review

N Garcia-Carbonero, W Li, M Cabeza-Morales… - International Journal of …, 2018 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of tumours, and its
incidence is rising worldwide. Although survival can be improved by surgical resection when …

Oxidative stress, disease and cancer

KK Singh - 2006 - books.google.com
This book aims to provide a comprehensive review of the most up-to-date knowledge of the
sources and molecular mechanisms of oxidative stress, and its role in disease and cancer. It …

Targeting redox metabolism in pancreatic cancer

N Abdel Hadi, G Reyes-Castellanos… - International journal of …, 2021 - mdpi.com
Cell metabolism is reprogrammed in cancer cells to meet their high bioenergetics and
biosynthetic demands. This metabolic reprogramming is accompanied by alterations in …

Oxidative stress affects the beginning of the growth of cancer cells through a variety of routes

EAM Saleh, F Al-Dolaimy, S Baymakov, MI Ullah… - … -Research and Practice, 2023 - Elsevier
Oxidative stress is a physiological condition that occurs when there is an imbalance
between the production of reactive oxygen species (ROS) and the cell's antioxidant defense …