The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: Acting …

C Song, CH Shieh, YS Wu, A Kalueff, S Gaikwad… - Progress in lipid …, 2016 - Elsevier
Omega-3 polyunsaturated fatty acids (n‐3-PUFAs), mainly eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA), may improve or prevent some psychiatric and …

Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

SC Dyall - Frontiers in aging neuroscience, 2015 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) exhibit neuroprotective properties and
represent a potential treatment for a variety of neurodegenerative and neurological …

Omega-3 polyunsaturated fatty acids and depression: a review of the evidence

R Liperoti, F Landi, O Fusco… - Current …, 2009 - ingentaconnect.com
Brain lipids contain a high proportion of polyunsaturated fatty acids (PUFA), which are a
main component of cell membranes. Omega-3 (ω-3) PUFA eicosapentaeoic acid (EPA) and …

[HTML][HTML] Omega-3 polyunsaturated fatty acids and oxylipins in neuroinflammation and management of Alzheimer disease

JG Devassy, S Leng, M Gabbs, M Monirujjaman… - Advances in …, 2016 - Elsevier
Alzheimer disease (AD) is becoming one of the most prevalent neurodegenerative
conditions worldwide. Although the disease progression is becoming better understood …

Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for …

A Borsini, A Nicolaou, D Camacho-Muñoz… - Molecular …, 2021 - nature.com
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can exert antidepressant,
anti-inflammatory and neuroprotective properties, but the exact molecular mechanism …

Neurological benefits of omega-3 fatty acids

SC Dyall, AT Michael-Titus - Neuromolecular medicine, 2008 - Springer
The central nervous system is highly enriched in long-chain polyunsaturated fatty acid
(PUFA) of the omega-6 and omega-3 series. The presence of these fatty acids as structural …

DHA/EPA (Omega-3) and LA/GLA (Omega-6) as bioactive molecules in neurodegenerative diseases

C Kousparou, M Fyrilla, A Stephanou… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases are characterized by neuroinflammation, neuronal depletion
and oxidative stress. They coincide with subtle chronic or flaring inflammation, sometimes …

The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease

M Belkouch, M Hachem, A Elgot, AL Van, M Picq… - The Journal of nutritional …, 2016 - Elsevier
Among omega-3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA, 22: 6n-
3) is important for adequate brain development and cognition. DHA is highly concentrated in …

Omega-3 polyunsaturated fatty acids in Alzheimer's disease: key questions and partial answers

F Calon - Current Alzheimer Research, 2011 - ingentaconnect.com
The current rise in the prevalence of Alzheimer's disease (AD) is unfortunately not matched
by new treatment options. In the last 10 years, epidemiological, preclinical and clinical data …

Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies

DW Luchtman, C Song - Neuropharmacology, 2013 - Elsevier
Omega-(n)-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA)
and eicosapentaenoic acid (EPA) are major components of neuronal membranes and have …