Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1–infected T cells

T Watanabe - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …

Integrated molecular analysis of adult T cell leukemia/lymphoma

K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi… - Nature …, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …

Genetic alterations in adult T‐cell leukemia/lymphoma

Y Kogure, K Kataoka - Cancer science, 2017 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATL) is a peripheral T‐cell neoplasm with a dismal
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …

[HTML][HTML] Molecular hallmarks of adult T cell leukemia

M Yamagishi, T Watanabe - Frontiers in microbiology, 2012 - frontiersin.org
The molecular hallmarks of adult T cell leukemia (ATL) comprise outstanding deregulations
of signaling pathways that control the cell cycle, resistance to apoptosis, and proliferation of …

Human T-cell leukemia virus type I at age 25: a progress report

M Matsuoka, KT Jeang - Cancer Research, 2005 - AACR
It has been 25 years since the discovery of human T-cell leukemia virus type I (HTLV-I) and
its role in adult T-cell leukemia. Here, in brief, we review the current state of our …

Human T-cell leukemia virus type I induces adult T-cell leukemia: from clinical aspects to molecular mechanisms

J Yasunaga, M Matsuoka - Cancer control, 2007 - journals.sagepub.com
Background Human T-cell leukemia virus type I (HTLV-I) is a causative virus of adult T-cell
leukemia (ATL), HTLV-I-associated myelopathy/tropical spastic paraparesis, and HTLV-I …

Polycomb-dependent epigenetic landscape in adult T-cell leukemia

D Fujikawa, S Nakagawa, M Hori… - Blood, The Journal …, 2016 - ashpublications.org
Adult T-cell leukemia-lymphoma (ATL) shows global gene expression alterations that confer
cellular characteristics and unfavorable prognosis. However, molecular mechanisms of the …

TCL1 Is Overexpressed in Patients Affected by Adult T-Cell Leukemias

MG Narducci, A Stoppacciaro, K Imada, T Uchiyama… - Cancer research, 1997 - AACR
Among mature postthymic T-cell leukemias, adult T-cell leukemia (ATL) has characteristic
clinicopathological entities. The association with the human T-cell leukemia/lymphotropic …

Whole-genome landscape of adult T-cell leukemia/lymphoma

Y Kogure, T Kameda, J Koya… - Blood, The Journal …, 2022 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive neoplasm immunophenotypically
resembling regulatory T cells, associated with human T-cell leukemia virus type-1. Here, we …

[HTML][HTML] Mechanisms of HTLV-1 persistence and transformation

M Boxus, L Willems - British journal of cancer, 2009 - nature.com
Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-
1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong …