Calcific aortic valve stenosis (CAVS) is common in the ageing population and set to become
an increasing economic and health burden. Once present, it inevitably progresses and has a …

Calcification occurs in atherosclerotic vascular lesions and in the aortic valve. Calcific aortic
valve disease (CAVD) is a slow, progressive disorder that ranges from mild valve thickening …

Calcific aortic valve disease (CAVD) increasingly afflicts our aging population. One third of
our elderly have echocardiographic or radiological evidence of calcific aortic valve sclerosis …

Calcific aortic valve stenosis is the result of regulated cell processes. The histological
hallmarks are inflammation and a remodelling of the extracellular matrix leading to bone …

Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

Calcific aortic valve disease (CAVD) is the most common heart valve disorder. There is no
medical treatment to prevent and/or promote the regression of CAVD. Hence, it is of foremost …

Calcific aortic valve disease (CAVD) is the most frequent heart valve disorder. It is
characterized by an active remodeling process accompanied with valve mineralization, that …

Calcific aortic valve disease (CAVD) encompasses the range of disease from initial
alterations in the cell biology of the leaflets to end-stage calcification resulting in left …

Calcific aortic valve disease (CAVD) is a major contributor to cardiovascular morbidity and
mortality and, given its association with age, the prevalence of CAVD is expected to continue …

Calcific aortic stenosis is the third most common cause of aortic valve disease in developed
countries. This condition increases in prevalence with advancing age, afflicting 2–3% of the …