Reverse vaccinology (RV) is a computational approach that aims to identify putative vaccine
candidates in the protein coding genome (proteome) of pathogens. RV has primarily been …

Reverse vaccinology (RV) is a bioinformatics approach that can predict antigens with
protective potential from the protein coding genomes of bacterial pathogens for subunit …

Reverse vaccinology defines the process of antigen discovery starting from genome
information. From its first application to Neisseria meningitidis group B, this approach has …

Most of the vaccines available today, albeit very effective, have been developed using
traditional “old-style” methodologies. Technologies developed in recent years have opened …

Reverse Vaccinology (RV) is a widely used approach to identify potential vaccine
candidates (PVCs) by screening the proteome of a pathogen through computational …

During the last century, several approaches have been used for the development of
vaccines, going from the immunization with live-attenuated bacteria up to the formulation of …

Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …

Background Since a milestone work on Neisseria meningitidis B, Reverse Vaccinology has
strongly enhanced the identification of vaccine candidates by replacing several …

Whole genome sequence data are increasingly available for a wide range of human
pathogens. The use of bioinformatic tools allows the comprehensive in silico screening of …

In this chapter, we review the computational approaches that have led to a new generation
of vaccines in recent years. There are many alternative routes to develop vaccines based on …