Cue reactivity is relevant across addictive disorders as a process relevant to maintenance,
relapse, and craving. Understanding the neurobiological foundations of cue reactivity across …

Chronic cocaine use is associated with enhanced cue reactivity to drug stimuli. However, it
may also alter functional connectivity (fcMRI) in regions involved in processing drug stimuli …

Background: Dysregulated striatal functioning coupled with executive control deficits arising
from abnormal frontal cortical function are considered key mechanisms in the development …

Neural biomarkers for the active detrimental effects of cocaine dependence (CD) are
lacking. Direct comparisons of brain connectivity in cocaine‐targeted networks between CD …

Abstract Alcohol Use Disorder has been associated with impairments of functional
connectivity between neural networks underlying reward processing and cognitive control …

Background: Addiction is a complex phenotype, though it consistently includes
characteristics of impulsivity. A number of brain regions are suggested to be involved in …

Importance Converging evidence has long identified both impulsivity and compulsivity as
key psychological constructs in drug addiction. Although dysregulated striatal-cortical …

Preclinical models have consistently demonstrated the importance of the mesocorticolimbic
(MCL) brain reward system in drug dependence, with critical molecular and cellular …

Brain imaging studies indicate that chronic cocaine users display altered functional
connectivity between prefrontal cortical, thalamic, striatal, and limbic regions; however, the …

Past research involving cocaine and resting-state functional connectivity (RSFC) has shown
altered functional connectivity within the frontal and between the frontal and other cortical …