[HTML][HTML] Enhancement of Immune Checkpoint Inhibitor-Mediated Anti-Cancer Immunity by Intranasal Treatment of Ecklonia cava Fucoidan against Metastatic Lung …

W Zhang, J Hwang, D Yadav, EK An, M Kwak… - International journal of …, 2021 - mdpi.com
Although fucoidan, a well-studied seaweed-extracted polysaccharide, has shown immune
stimulatory effects that elicit anticancer immunity, mucosal adjuvant effects via intranasal …

Comparison of the immune activation capacities of fucoidan and laminarin extracted from Laminaria japonica

EK An, J Hwang, SJ Kim, HB Park, W Zhang… - International Journal of …, 2022 - Elsevier
Laminaria japonica is a brown alga and is composed primarily of polysaccharides. Fucoidan
and laminarin are the major polysaccharides of L. japonica and exhibit biological activities …

Dendritic cell-mediated cancer immunotherapy with Ecklonia cava fucoidan

HB Park, J Hwang, SM Lim, W Zhang, JO Jin - International Journal of …, 2020 - Elsevier
Fucoidan is known to exert immunomodulatory effects in animals and humans. Here, we
extracted fucoidan from Ecklonia cava (ECF) and evaluated its immunostimulatory and …

[HTML][HTML] Dendritic cell and cancer therapy

D Galati, S Zanotta - International Journal of Molecular Sciences, 2023 - mdpi.com
Dendritic cells (DCs) are acknowledged as the most potent professional antigenpresenting
cells (APCs), able to induce adaptive immunity and support the innate immune response. In …

[HTML][HTML] Intranasal Administration of Codium fragile Polysaccharide Elicits Anti-Cancer Immunity against Lewis Lung Carcinoma

Y Wang, EK An, SJ Kim, SG You, JO Jin - International Journal of …, 2021 - mdpi.com
Natural polysaccharides have shown promising effects on the regulation of immunity in
animals. In this study, we examined the immune stimulatory effect of intranasally …

[HTML][HTML] In vivo immunomodulatory activity of fucoidan from brown alga Undaria pinnatifida in sarcoma 180-bearing mice

Q Li, X Wang, Y Wan, X Hu, J Liu, J Wang - Journal of Functional Foods, 2023 - Elsevier
Bioactivities of fucoidan, a class of marine algal polysaccharides, vary depending on the
original algal species. The aim of this study was to explore the in vivo immunomodulatory …

Ecklonia cava fucoidan has potential to stimulate natural killer cells in vivo

W Zhang, EK An, HB Park, J Hwang… - International Journal of …, 2021 - Elsevier
Fucoidan is a sulfated polysaccharide, derived from various marine brown seaweeds, that
has immunomodulatory effects. In this study, we analyzed the effects of five different …

[HTML][HTML] Systemic Immunomodulatory Effects of Codonopsis pilosula Glucofructan on S180 Solid-Tumor-Bearing Mice

Y Fan, Y Long, Y Gong, X Gao, G Zheng… - International Journal of …, 2023 - mdpi.com
The immune functions of the body are intricately intertwined with the onset and
advancement of tumors, and immunotherapy mediated by bioactive compounds has …

[HTML][HTML] Fucoidan can function as an adjuvant in vivo to enhance dendritic cell maturation and function and promote antigen-specific T cell immune responses

JO Jin, W Zhang, JY Du, KW Wong, T Oda, Q Yu - PloS one, 2014 - journals.plos.org
Fucoidan, a sulfated polysaccharide purified from brown algae, has a variety of immune-
modulation effects, including promoting antigen uptake and enhancing anti-viral and anti …

[HTML][HTML] Selective suppression of cell growth and programmed cell death-ligand 1 expression in HT1080 fibrosarcoma cells by low molecular weight fucoidan extract

K Teruya, Y Kusumoto, H Eto, N Nakamichi… - Marine drugs, 2019 - mdpi.com
Low molecular weight fucoidan extract (LMF), prepared by an abalone glycosidase
digestion of a crude fucoidan extracted from Cladosiphon novae-caledoniae Kylin, exhibits …