This work uses finite element models of fluid flow to reveal new mechanisms for normalizing
the phenotype of engineered microvasculature in vitro, and to design networks of …

Engineered microvasculature, tissue engineered blood vessels, tissue engineering, tissue
vascularization Keywords: engineered microvasculature; tissue engineered blood vessels; …

This thesis focuses on the development of methods to create stable microvascular structures
using miniaturised devices containing microchannels and water-swollen networks known as …

This paper reports the fabrication of compliant and permeable thin films with controlled
curvature preferable to serve as engineering scaffolds for the production of in vivo like …

Highlights•Microfluidic biomaterials enable immediate perfusion of an engineered
tissue.•Mechanical stresses govern the long-term vascular stability in these materials.• …

The ability of generate new microvessels in desired numbers and at desired locations has
been a long-sought goal in vascular medicine, engineering, and biology. Historically, the …

One of the principal challenges in the tissue engineering and regenerative medicine has
been the need for establishment of a functional vasculature for engineered tissues and …

The directed or de novo formation of microvasculature in engineered tissue constructs is
essential for accurately replicating physiological function. A limiting factor of a system relying …

The microvasculature is an extensive, heterogeneous, and complex system that plays a
critical role in human physiology and disease. It nourishes almost all living human cells and …

The gap between in vitro and in vivo assays has inspired biomimetic model development.
Tissue engineered models that attempt to mimic the complexity of microvascular networks …