Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase‐2 induction by capsaicin and related analogs in macrophages
CW Chen, ST Lee, WT Wu, WM Fu… - British journal of …, 2003 - Wiley Online Library
Although capsaicin analogs might be a potential strategy to manipulate inflammation, the
mechanism is still unclear. In this study, the effects and action mechanisms of vanilloid …
mechanism is still unclear. In this study, the effects and action mechanisms of vanilloid …
Capsazepine, a vanilloid receptor antagonist, inhibits the expression of inducible nitric oxide synthase gene in lipopolysaccharide-stimulated RAW264. 7 …
GS Oh, HO Pae, WG Seo, NY Kim, KH Pyun… - International …, 2001 - Elsevier
High amounts of nitric oxide (NO) production following the induction of inducible NO
synthase (iNOS) gene expression has been implicated in the pathogenesis of inflammatory …
synthase (iNOS) gene expression has been implicated in the pathogenesis of inflammatory …
Nonivamide, a capsaicin analogue, exhibits anti‐inflammatory properties in peripheral blood mononuclear cells and U‐937 macrophages
J Walker, JP Ley, J Schwerzler, B Lieder… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Inflammation‐related diseases are a worldwide problem. The counteraction of
inflammation with compounds activating the trigeminal nerve is one strategy to fight these …
inflammation with compounds activating the trigeminal nerve is one strategy to fight these …
Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages
CS Kim, T Kawada, BS Kim, IS Han, SY Choe, T Kurata… - Cellular signalling, 2003 - Elsevier
Capsaicin, a major ingredient of hot pepper, was considered to exhibit an anti-inflammatory
property. In order to clarify the signalling mechanism underlying the anti-inflammatory action …
property. In order to clarify the signalling mechanism underlying the anti-inflammatory action …
Native Australian fruit polyphenols inhibit COX-2 and iNOS expression in LPS-activated murine macrophages
Purified polyphenolic-rich extracts from four native Australian fruits, Illawarra Plum
(Podocarpus elatus Endl., Podocarpaceae), Kakadu Plum (Terminalia ferdinandiana Exell …
(Podocarpus elatus Endl., Podocarpaceae), Kakadu Plum (Terminalia ferdinandiana Exell …
Anti‐Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT‐1 and NF‐κB Activations, Whereas Flavone, Isorhamnetin, Naringenin …
M Hämäläinen, R Nieminen, P Vuorela… - Mediators of …, 2007 - Wiley Online Library
In inflammation, bacterial products and proinflammatory cytokines induce the formation of
large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds …
large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds …
Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and Iκ-B phosphorylation in RAW 264.7 macrophage cells
Cardamonin, a chalcone isolated from the fruits of a local plant Alpinia rafflesiana, has
demonstrated anti-inflammatory activity in cellular models of inflammation. In this report, we …
demonstrated anti-inflammatory activity in cellular models of inflammation. In this report, we …
Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages
TL Wadsworth, DR Koop - Biochemical pharmacology, 1999 - Elsevier
The beneficial effects of moderate red wine consumption have been attributed, in part, to the
presence of antioxidant components. Oxidant stress is an activating stimulus for the NF …
presence of antioxidant components. Oxidant stress is an activating stimulus for the NF …
Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-κB, ERK1/2, and p38 kinase
CY Choi, KR Park, JH Lee, YJ Jeon, KH Liu… - European journal of …, 2007 - Elsevier
Isoeugenol, which is a naturally occurring o-methoxyphenol in a variety of foods and
essential oils, is known to have anti-inflammatory effects, although the mechanism is not …
essential oils, is known to have anti-inflammatory effects, although the mechanism is not …
Anti-inflammatory activity of extracts from fruits, herbs and spices
M Mueller, S Hobiger, A Jungbauer - Food chemistry, 2010 - Elsevier
Inflammation plays an important role in various diseases with high prevalence within
populations such as rheumatoid arthritis, atherosclerosis and asthma. Here we demonstrate …
populations such as rheumatoid arthritis, atherosclerosis and asthma. Here we demonstrate …