The acquisition of cancer hallmarks requires molecular alterations at multiple levels
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …

With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

The manifestations of cancerous phenotypes necessitate alterations at different levels of
information-flow from genome to proteome. The molecular alterations at different information …

Cancer is the manifestation of abnormalities of different physiological processes involving
genes, DNAs, RNAs, proteins, and other biomolecules whose profiles are reflected in …

The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …

While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …

Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

Cancer is the quintessential complex disease. As technologies evolve faster each day, we
are able to quantify the different layers of biological elements that contribute to the …

This chapter discusses general concepts on the generation of omics data, along with
available strategies for multi-omics data analysis and integration in the context of clinical …