Oxidative stress-induced inflammation in susceptible airways by anthropogenic aerosol

Z Leni, LE Cassagnes, KR Daellenbach, I El Haddad… - PLoS …, 2020 - journals.plos.org
Ambient air pollution is one of the leading five health risks worldwide. One of the most
harmful air pollutants is particulate matter (PM), which has different physical characteristics …

Lung toxicity of particulates and gaseous pollutants using ex-vivo airway epithelial cell culture systems

R Lakhdar, S Mumby, H Abubakar-Waziri, A Porter… - Environmental …, 2022 - Elsevier
Air pollution consists of a multi-faceted mix of gases and ambient particulate matter (PM)
with diverse organic and non-organic chemical components that contribute to increasing …

Direct and indirect air particle cytotoxicity in human alveolar epithelial cells

NS Orona, F Astort, GA Maglione, PHN Saldiva… - Toxicology in Vitro, 2014 - Elsevier
Air particulate matter has been associated with adverse impact on the respiratory system
leading to cytotoxic and proinflammatory effects. The biological mechanisms behind these …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Role of size and composition of traffic and agricultural aerosols in the molecular responses triggered in airway epithelial cells

V Stéphanie, M Laurent, C Hélène… - Inhalation …, 2011 - Taylor & Francis
The increased levels of fine particles in the atmosphere are suspected of aggravating
cardiopulmonary diseases, but the determinants of particle toxicity are poorly understood …

Gene expression profiling and pathway analysis of human bronchial epithelial cells exposed to airborne particulate matter collected from Saudi Arabia

H Sun, M Shamy, T Kluz, AB Muñoz, M Zhong… - Toxicology and applied …, 2012 - Elsevier
Epidemiological studies have established a positive correlation between human mortality
and increased concentration of airborne particulate matters (PM). However, the mechanisms …

Prooxidant and Proinflammatory Potency of Air Pollution Particulate Matter (PM2.5–0.3) Produced in Rural, Urban, or Industrial Surroundings in Human Bronchial …

M Dergham, C Lepers, A Verdin, S Billet… - Chemical research in …, 2012 - ACS Publications
Compelling evidence indicates that exposure to air pollution particulate matter (PM) affects
human health. However, how PM composition interacts with PM-size to cause adverse …

[HTML][HTML] Variations in reactive oxygen species generation by urban airborne particulate matter in lung epithelial cells—Impact of inorganic fraction

O Mazuryk, G Stochel, M Brindell - Frontiers in chemistry, 2020 - frontiersin.org
Air pollution is associated with numerous negative effects on human health. The toxicity of
organic components of air pollution is well-recognized, while the impact of their inorganic …

Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies

S Becker, S Mundandhara, RB Devlin… - Toxicology and applied …, 2005 - Elsevier
In order to better understand how ambient air particulate matter (PM) affect lung health, the
two main airway cell types likely to interact with inhaled particles, alveolar macrophages …

Temporal–spatial variations of the physicochemical characteristics of air pollution Particulate Matter (PM2. 5–0.3) and toxicological effects in human bronchial …

M Dergham, C Lepers, A Verdin, F Cazier, S Billet… - Environmental …, 2015 - Elsevier
While the evidence for the health adverse effects of air pollution Particulate Matter (PM) has
been growing, there is still uncertainty as to which constituents within PM are most harmful …