Tooth enamel develops within a pH sensitive amelogenin-rich protein matrix. The purpose of
the present study is to shed light on the intimate relationship between enamel matrix pH …

During enamel formation, the organic enamel protein matrix interacts with calcium
phosphate minerals to form elongated, parallel, and bundled enamel apatite crystals of …

The self-assembly of the predominant extracellular enamel matrix protein amelogenin plays
an essential role in regulating the growth and organization of enamel mineral during early …

The extracellular tooth enamel matrix is a unique, protein-rich environment that provides the
structural basis for the growth of long and parallel oriented enamel crystals. Here we have …

Unlike other mineralized tissues, mature dental enamel is primarily (> 95% by weight)
composed of apatitic crystals and has a unique hierarchical structure. Due to its high mineral …

Macromolecular assembly of extracellular enamel matrix proteins (EMPs) is intimately
associated with the nucleation, growth, and maturation of highly organized hydroxyapatite …

Abstract Authors–Paine ML, Snead ML Dental enamel is a composite bioceramic material
that is the hardest tissue in the vertebrate body, containing long, thin crystallites of …

Amelogenins, the major protein component of the mineralizing enamel extracellular matrix
are critical for normal enamel formation as documented in the linkage studies of a group of …

Enamel formation is a powerful model for the study of biomineralization. A key feature
common to all biomineralizing systems is their dependency upon the biosynthesis of an …

Enamel matrix proteins, including the most abundant amelogenin and lesser amounts of
enamelin, ameloblastin, and proteinases, play vital roles in controlling crystal nucleation and …