Taurine protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis

J Das, J Ghosh, P Manna, PC Sil - Amino acids, 2012 - Springer
The protective effect of taurine against doxorubicin-induced testicular oxidative stress and
apoptosis was investigated in rats. Male rats 8 weeks of age were treated with doxorubicin …

Taurine increases testicular function in aged rats by inhibiting oxidative stress and apoptosis

J Yang, X Zong, G Wu, S Lin, Y Feng, J Hu - Amino acids, 2015 - Springer
In males, the decline of androgen synthesis, spermatogenesis and sexual function are the
main phenotypes of aging, which may be attributed to testicular dysfunction. Taurine can act …

Taurine protects rat testes against NaAsO2-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways

J Das, J Ghosh, P Manna, M Sinha, PC Sil - Toxicology letters, 2009 - Elsevier
Arsenic (As) is a well known toxicity inducer. Recent investigations, however, showed that it
might have some therapeutic application in cancer treatment. These dual roles of arsenic …

Ameliorative effect of taurine-chloramine in azathioprine-induced testicular damage; a deeper insight into the mechanism of protection

MF Schaalan, BK Ramadan… - BMC complementary and …, 2018 - Springer
Background The male reproductive system is a sensitive and intricate process that can be
distressed following exposure to various toxicants. Therapeutic drugs, especially …

Protective role of taurine against genotoxic damage in mice treated with methotrexate and tamoxfine

SS Alam, NA Hafiz, AH Abd El-Rahim - Environmental toxicology and …, 2011 - Elsevier
The genotoxic actions of anti-neoplastic drugs can lead to the development of secondary
cancers in patients in extended remission. One of the most attractive approaches to disease …

Amelioration of nandrolone decanoate-induced testicular and sperm toxicity in rats by taurine: effects on steroidogenesis, redox and inflammatory cascades, and …

MAE Ahmed - Toxicology and applied pharmacology, 2015 - Elsevier
The wide abuse of the anabolic steroid nandrolone decanoate by athletes and adolescents
for enhancement of sporting performance and physical appearance may be associated with …

Protective effect of Gallic acid on doxorubicin‐induced testicular and epididymal toxicity

MJ Olusoji, OM Oyeyemi, ER Asenuga… - Andrologia, 2017 - Wiley Online Library
The effect of Gallic acid (GA) on doxorubicin (DOX)‐induced testicular and epididymal
toxicity was investigated in experimental rat model. The rats were randomly divided into six …

[PDF][PDF] Taurine protects mouse spermatocytes from ionizing radiation-induced damage through activation of Nrf2/HO-1 signaling

W Yang, J Huang, B Xiao, Y Liu, Y Zhu… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: The increasing prevalence of ionizing radiation exposure has
inevitably raised public concern over the potential detrimental effects of ionizing radiation on …

The role of taurine in male reproduction: Physiology, pathology and toxicology

Y Li, Q Peng, J Shang, W Dong, S Wu, X Guo… - Frontiers in …, 2023 - frontiersin.org
Taurine, a sulfur-containing amino acid, has a wide range of biological effects, such as bile
salt formation, osmotic regulation, oxidative stress inhibition, immunomodulation and …

Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats

SM Wei, ZZ Yan, J Zhou - Urology, 2007 - Elsevier
OBJECTIVES: To evaluate the effect of taurine, a potent antioxidant, on testicular ischemia-
reperfusion injury due to excess reactive oxygen species produced by neutrophils after …