We have recently published the notion of the “vitals” of Parkinson's, a conglomeration of
signs and symptoms, largely nonmotor, that must not be missed and yet often not considered …

The vitals of Parkinson's disease (PD) address the often-ignored symptoms, which are
considered either peripheral to the central core of motor symptoms of PD or secondary …

Parkinson's disease (PD) has become the second most common neurodegenerative
condition following Alzheimer's disease (AD), exhibiting high prevalence and incident rates …

Abstract See Breen and Lang (doi: 10.1093/aww321) for a scientific commentary on this
article. At the time of clinical diagnosis, patients with Parkinson's disease already have a …

Background Digital tools such as wearable sensors may help to monitor Parkinson's disease
(PD) in daily life. To optimally achieve the expected benefits, such as personized care and …

Measurement of disease state is essential in both clinical practice and research in order to
assess the severity and progression of a patient's disease status, effect of treatment, and …

Clinical disease milestones (literally a stone functioning as a milepost in ancient Rome; in
medical sciences, a significant event or stage in disease progression) are clinically relevant …

To 'measure'entails the quantification of something by comparison with a fixed magnitude of
the same species taken as the unit. This way, the attribute to be measured must be directly …

Parkinson disease (PD) is a common neurodegenerative condition. Typically beginning in
the sixth or seventh decade of life, it is characterized by the unilateral onset of resting tremor …

Parkinson's disease (PD), a progressive and disabling condition, is the second most
common neurodegenerative disorder. There is currently no clinically available biomarker in …