Mapping the activity of the human mesolimbic dopamine system by BOLD-fMRI is a tempting
approach to non-invasively study the action of the brain reward system during different …

Neuromodulators determine how neural circuits process information during cognitive states
such as wakefulness, attention, learning, and memory [1]. fMRI can provide insight into their …

Functional neuroimaging (fMRI) studies show activation in mesolimbic circuitry in tasks
involving reward processing, like the Monetary Incentive Delay Task (MIDT). In voltammetry …

Controversial results have been reported concerning the neural mechanisms involved in the
processing of rewards and punishments. On the one hand, there is evidence suggesting that …

Dopamine release in cortical and subcortical structures plays a central role in reward-related
neural processes. Within this context, dopaminergic inputs are commonly assumed to play …

Abstract Evaluation of the magnitudes of intrinsically rewarding stimuli is essential for
assigning value and guiding behavior. By combining parametric manipulation of a primary …

Human functional magnetic resonance imaging (fMRI) studies, as well as lesion, drug, and
single-cell recording studies in animals, suggest that the striatum plays a key role in …

Invasive recording of dopamine neurons in the substantia nigra and ventral tegmental area
(SN/VTA) of behaving animals suggests a role for these neurons in reward learning and …

Ascending dopaminergic projections from neurons located in the Ventral Tegmental Area
(VTA) are key to the etiology, dysfunction, and control of motivation, learning, and addiction …

Processing of reward and salience without reward association are known to critically rely on
the dopamine system. A growing body of evidence from animal studies suggests that both …