Objective—Pseudoxanthoma elasticum is an inherited metabolic disorder resulting from
ABCC6 gene mutations. It is characterized by progressive calcification and fragmentation of …

Pseudoxanthoma elasticum (PXE) is a heritable disorder of connective tissue, affecting
mainly skin, eye and the cardiovascular system. PXE is characterized by dystrophic …

Vascular calcification is a complex and dynamic process occurring in various physiological
conditions such as aging and exercise or in acquired metabolic disorders like diabetes or …

Pseudoxanthoma elasticum (PXE), a multisystem heritable disorder with aberrant
mineralization of arterial blood vessels, is caused by mutations in the ABCC6 gene …

Background and aims Pseudoxanthoma elasticum (PXE) is caused by variants in the
ABCC6 gene. It results in calcification in the skin, peripheral arteries and the eyes, but has …

Pseudoxanthoma elasticum (PXE) is a heritable disorder characterized by ectopic
calcification of connective tissue in skin, Bruch's membrane of the eye, and walls of blood …

Arterial calcification is a common feature of pseudoxanthoma elasticum (PXE), a disease
characterized by ABCC6 mutations, inducing a deficiency in pyrophosphate, a key inhibitor …

Pseudoxanthoma elasticum (PXE), a rare recessive genetic disease causing skin, eye, and
cardiovascular lesions, is characterized by the calcification of elastic fibers. The disorder is …

Mutations in the ABCC6 gene cause soft-tissue calcification in pseudoxanthoma elasticum
(PXE) and, in some patients, generalized arterial calcification of infancy (GACI). PXE is …

Pseudoxanthoma elasticum (PXE), a rare genetic disease caused by mutations in the
ABCC6 gene, is characterized by progressive calcification of elastic fibers in the skin, eyes …