Myocardial ischaemia reperfusion injury is the leading cause of death in patients with
cardiovascular disease. Interventions such as ischaemic pre and postconditioning protect …

The mechanisms by which ischaemia reperfusion injury can be influenced have been the
subject of extensive research in the last decades. Early restoration of arterial blood flow and …

Anaesthetists are confronted on a daily basis with patients with coronary artery disease,
myocardial ischaemia, or both during the perioperative period. Therefore, prevention and …

SummaryA variety of laboratory and clinical studies clearly indicate that exposure to
anaesthetic agents can lead to a pronounced protection of the myocardium against …

In the 30 years since the original description of ischaemic preconditioning, understanding of
the pathophysiology of ischaemia/reperfusion injury and concepts of cardioprotection have …

The pharmacological conditioning of the heart with anaesthetics, such as volatile
anaesthetics or opioids, is a phenomenon whereby a transient exposure to an anaesthetic …

Cardioprotection encompasses a variety of strategies protecting the heart against
myocardial injury that occurs during and after inadequate blood supply to the heart during …

INTRODUCTION Acute ST-elevation myocardial infarction (STEMI) is characterised by
unpredictable epicardial artery occlusion. The myocardium supplied by the vessel is …

The aim of pharmacological conditioning is to protect the heart against myocardial ischemia-
reperfusion (I/R) injury and its consequences. There is extensive literature that reports a …

Experimental evidence has clearly demonstrated that volatile anaesthetic agents have direct
protective properties against reversible and irreversible ischaemic myocardial damage …