[HTML][HTML] Tissue and plasma proteomic profiling indicates AHSG as a potential biomarker for ascending thoracic aortic aneurysms

R Kazamia, A Keravnou, A Moushi, K Sokratous… - BMC cardiovascular …, 2023 - Springer
Abstract Background Thoracic Aortic Aneurysms (TAAs) develop asymptomatically and are
characterized by dilatation of the aorta. This is considered a life-threatening vascular …

[HTML][HTML] Targeted proteomic analysis of patients with ascending thoracic aortic aneurysm

A Daskalopoulou, SG Giotaki, K Toli, A Minia, V Pliaka… - Biomedicines, 2023 - mdpi.com
Background: There is a need for clinical markers to aid in the detection of individuals at risk
of harboring an ascending thoracic aneurysm (ATAA) or developing one in the future …

[HTML][HTML] Proteomic profiling for the identification of serum diagnostic biomarkers for abdominal and thoracic aortic aneurysms

K Satoh, T Maniwa, T Oda, K Matsumoto - Proteome Science, 2013 - Springer
Background Aortic aneurysm is an increasingly common vascular disorder with fatal
implication. However, there is no established diagnosis other than that based on …

Biological features of thoracic aortic diseases. Where are we now, where are we heading to: established and emerging biomarkers and molecular pathways

A Parolari, E Tremoli, P Songia, A Pilozzi… - European Journal of …, 2013 - academic.oup.com
Thoracic aortic aneurysms (TAAs) and aortic dissections (ADs) are among the main causes
of mortality and morbidity in Western countries. For this reason, the diagnosis, prevention …

[HTML][HTML] Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression

H Yagi, M Nishigori, Y Murakami, T Osaki, S Muto… - Scientific reports, 2020 - nature.com
Since aortic aneurysms (AAs) are mostly asymptomatic, but they have a high mortality rate
upon rupture, their detection and progression evaluation are clinically important issues. To …

[HTML][HTML] Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease

JS Ikonomidis, CR Ivey, JB Wheeler… - The Journal of thoracic …, 2013 - Elsevier
BACKGROUND: Thoracic aortic aneurysms (TAAs) develop through an asymptomatic
process resulting in gross dilation that progresses to rupture if left undetected and untreated …

Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm

KM Black, A Masuzawa, RC Hagberg… - Journal of the …, 2013 - Am Heart Assoc
Background Human ascending thoracic aortic aneurysms (ATAAs) are life threatening and
constitute a leading cause of mortality in the United States. Previously, we demonstrated that …

[HTML][HTML] Hypothesis-free secretome analysis of thoracic aortic aneurysm reinforces the central role of TGF-β cascade in patients with bicuspid aortic valve

S Rocchiccioli, A Cecchettini, P Panesi, PA Farneti… - Journal of …, 2017 - Elsevier
Background Ascending thoracic aortic aneurysm (ATAA) is a major cause of morbidity and
mortality worldwide. The pathogenesis of medial degeneration of the aorta remains …

Biomarkers in TAA—the holy grail

GHW van Bogerijen, JL Tolenaar, V Grassi… - Progress in …, 2013 - Elsevier
Thoracic aortic aneurysm (TAA) is a silent disease, often discovered at a time point that
dramatic complications, as rupture and dissection, occur. For the detection of asymptomatic …

Is there a role for biomarkers in thoracic aortic aneurysm disease?

D Balmforth, A Harky, B Adams, J Yap… - General thoracic and …, 2019 - Springer
Thoracic aortic aneurysm (TAA) represents a major cause of mortality and morbidity in
Western countries. The natural history of TAA is indolent, with patients usually being …