Oral squamous cell carcinoma: Key clinical questions, biomarker discovery, and the role of proteomics

UU Malik, S Zarina, SR Pennington - Archives of oral biology, 2016 - Elsevier
Background The molecular and cellular mechanisms underlying the pathogenesis of oral
squamous cell carcinoma (OSCC) are relatively poorly understood and remain a subject of …

Oral cancer: deregulated molecular events and their use as biomarkers

N Sinevici, J O'sullivan - Oral oncology, 2016 - Elsevier
Oral Cancer (OC) is a subset of head and neck cancer (HNC) with an annual worldwide
incidence of 275,000 cases. OC remains a significant burden worldwide in terms of …

Understanding the complex pathogenesis of oral cancer: A comprehensive review

M Georgaki, VI Theofilou, E Pettas, E Stoufi… - Oral surgery, oral …, 2021 - Elsevier
The pathogenesis of oral cancer is a complex and multifactorial process that requires a deep
understanding of the underlying mechanisms involved in the development and progress of …

Molecular diagnostics in oral cancer and oral potentially malignant disorders—A clinician's guide

T Yap, A Celentano, C Seers… - Journal of Oral …, 2020 - Wiley Online Library
Current risk stratification of individuals for the development of oral squamous cell carcinoma
(OSCC), including those with oral potentially malignant disorders (OPMD), remains based …

[HTML][HTML] Recent trends in predictive biomarkers for determining malignant potential of oral potentially malignant disorders

GS Sarode, SC Sarode, N Maniyar, N Sharma… - Oncology …, 2019 - ncbi.nlm.nih.gov
Despite of the tremendous advancements in the field of cancer prevention, detection and
treatment, the overall prognosis of oral squamous cell carcinoma (OSCC) still remains poor …

Emerging histological and serological biomarkers in oral squamous cell carcinoma: Applications in diagnosis, prognosis evaluation and personalized therapeutics

L Pekarek, MJ Garrido‑Gil… - Oncology …, 2023 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity
and accounts for> 90% of all oral cancers. Despite advances in diagnostic procedures and …

Biomarkers of oral premalignant epithelial lesions for clinical application

R Mishra - Oral oncology, 2012 - Elsevier
Oral cancer is the sixth most common form of cancer worldwide, and the majority of cases
occur in India and Southeast Asia. Its major risk factors in the western world include smoking …

[HTML][HTML] Essentials of oral cancer

C Rivera - International journal of clinical and experimental …, 2015 - ncbi.nlm.nih.gov
Oral cancer is one of the 10 most common cancers in the world, with a delayed clinical
detection, poor prognosis, without specific biomarkers for the disease and expensive …

Disease mechanism and biomarkers of oral squamous cell carcinoma

BMN Brinkman, DTW Wong - Current opinion in oncology, 2006 - journals.lww.com
Important progress has been made in the molecular understanding of oral cancer and its
application for diagnosis, prognosis and treatment. The increased efforts in translational …

Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …