Nitro fatty acids (NFAs) are endogenously generated lipid mediators deriving from reactions
of unsaturated electrophilic fatty acids with reactive nitrogen species. Furthermore …

Nitroalkene fatty acids can be formed in vivo and administered exogenously. They exert
pleiotropic signaling actions with cytoprotective and antiinflammatory effects. The presence …

Unsaturated nitro fatty acids (NO2-FAs) constitute a category of molecules that may be
formed endogenously by the reaction of unsaturated fatty acids (UFAs) with secondary …

Fatty acid nitroalkene derivatives (NO2-FA) activate Nrf2-regulated antioxidant gene
expression and inhibit NF-κB-dependent cytokine expression. To better define NO2-FA …

Significance: Nitrated derivatives of unsaturated fatty acids (nitro-fatty acids) are being
formed and detected in human plasma, cell membranes, and tissue, triggering signaling …

Fatty acid nitroalkenes (NO 2-FA) are endogenously-generated products of the reaction of
metabolic and inflammatory-derived nitrogen dioxide (. NO 2) with unsaturated fatty acids …

Electrophilic fatty acid nitroalkenes (NO 2-FA) are products of nitric oxide and nitrite-
mediated unsaturated fatty acid nitration. These electrophilic products induce pleiotropic …

Redox-sensitive posttranslational modification emerged as important signaling mechanisms.
Besides other posttranslational modifications nitroalkylation by nitrated fatty acids mediate …

Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue,
modulating metabolic as well as inflammatory signaling pathways. Here we discuss the …

Foundational advances in eicosanoid signaling, the free radical biology of oxygen and nitric
oxide and mass spectrometry all converged to enable the discovery of nitrated unsaturated …