Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats

M Egawa, H Yoshimatsu… - American Journal of …, 1991 - journals.physiology.org
To investigate the effects of neuropeptide Y (NPY) on sympathetic nerve activity to
interscapular brown adipose tissue (IBAT), we injected NPY into the third cerebroventricle …

Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity

N Zarjevski, I Cusin, R Vettor… - …, 1993 - academic.oup.com
Chronic intracerebroventricular (icv) administration of neuropeptide-Y (NPY; 10
micrograms/day) was performed in normal female rats to investigate its hormonal and …

Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism

CJ Billington, JE Briggs, S Harker… - American Journal of …, 1994 - journals.physiology.org
Intracerebroventricular injection of neuropeptide Y (NPY) has two effects on energy
metabolism in addition to increased feeding: decreased brown fat thermogenesis and …

Effect of corticotropin releasing hormone and neuropeptide Y on electrophysiological activity of sympathetic nerves to interscapular brown adipose tissue

M Egawa, H Yoshimatsu, GA Bray - Neuroscience, 1990 - Elsevier
It has been proposed that there is a reciprocal relationship between food intake and
sympathetic activity. To test this hypothesis corticotropin releasing hormone, which …

Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism

CJ Billington, JE Briggs, M Grace… - American Journal of …, 1991 - journals.physiology.org
Our objective was to find out if central injection of neuropeptide Y (NPY) would alter brown
fat thermogenesis and white fat lipoprotein lipase activity. The following three groups of …

Secretion of neuropeptide Y in human adipose tissue and its role in maintenance of adipose tissue mass

K Kos, AL Harte, S James, DR Snead… - American Journal …, 2007 - journals.physiology.org
NPY is an important central orexigenic hormone, but little is known about its peripheral
actions in human adipose tissue (AT) or its potential paracrine effects. Our objective was to …

Increased neuropeptide Y secretion in the hypothalamic paraventricular nucleus of obese (fa/fa) Zucker rats

S Dryden, L Pickavance, HM Frankish, G Williams - Brain research, 1995 - Elsevier
NPY is synthesized in the hypothalamic arcuate nucleus (ARC), and NPY injected into the
paraventricular nucleus (PVN), the main site of NPY release, induces hyperphagia and …

Hypothalamic neuropeptide Y (NPY) controls hepatic VLDL-triglyceride secretion in rats via the sympathetic nervous system

E Bruinstroop, L Pei, MT Ackermans, E Foppen… - Diabetes, 2012 - Am Diabetes Assoc
Excessive secretion of triglyceride-rich very low-density lipoproteins (VLDL-TG) contributes
to diabetic dyslipidemia. Earlier studies have indicated a possible role for the hypothalamus …

Intracerebroventricular administration of neuropeptide Y to normal rats increases obese gene expression in white adipose tissue

A Sainsbury, I Cusin, P Doyle, F Rohner-Jeanrenaud… - Diabetologia, 1996 - Springer
The aim of this work was to determine the possible inter-relationship between neuropeptide
Y (NPY, a hypothalamic stimulator of feeding) and adipose tissue expression of the ob …

Adrenalectomy prevents the obesity syndrome produced by chronic central neuropeptide Y infusion in normal rats

A Sainsbury, I Cusin, F Rohner-Jeanrenaud… - Diabetes, 1997 - Am Diabetes Assoc
Neuropeptide Y (NPY) in the hypothalamus plays an important role in the regulation of food
intake and body weight and seems to be implicated in the etiology of obesity. When …