A Novel In Vivo Model of Laryngeal Papillomavirus-Associated Disease Using Mus musculus Papillomavirus

RE King, A Bilger, J Rademacher, ET Ward-Shaw… - Viruses, 2022 - mdpi.com
Recurrent respiratory papillomatosis (RRP), caused by laryngeal infection with low-risk
human papillomaviruses, has devastating effects on vocal communication and quality of life …

The Larynx is Protected from Secondary and Vertical Papillomavirus Infection in Immunocompetent Mice

RE King, J Rademacher, ET Ward‐Shaw… - The …, 2024 - Wiley Online Library
Objective Mouse papillomavirus MmuPV1 causes both primary and secondary infections of
the larynx in immunocompromised mice. Understanding lateral and vertical transmission of …

Preclinical models of laryngeal papillomavirus infection: a scoping review

RE King, A Bilger, J Rademacher… - The …, 2023 - Wiley Online Library
Objective Laryngeal human papillomavirus (HPV) infection causes recurrent respiratory
papillomatosis (RRP) and accounts for up to 25% of laryngeal cancers. Lack of satisfactory …

An infection-based murine model for papillomavirus-associated head and neck cancer

T Wei, D Buehler, E Ward-Shaw, PF Lambert - MBio, 2020 - Am Soc Microbiol
Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-
risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous …

Secondary infections, expanded tissue tropism, and evidence for malignant potential in immunocompromised mice infected with Mus musculus papillomavirus 1 DNA …

NM Cladel, LR Budgeon, TK Cooper… - Journal of …, 2013 - Am Soc Microbiol
Papillomavirus disease poses a special challenge to people with compromised immune
systems. Appropriate models to study infections in these individuals are lacking. We report …

Mus musculus papillomavirus 1: a new frontier in animal models of papillomavirus pathogenesis

ME Spurgeon, PF Lambert - Journal of virology, 2020 - Am Soc Microbiol
Animal models of viral pathogenesis are essential tools in human disease research. Human
papillomaviruses (HPVs) are a significant public health issue due to their widespread sexual …

Mouse papillomavirus infections spread to cutaneous sites with progression to malignancy

NM Cladel, LR Budgeon, TK Cooper… - Journal of General …, 2017 - microbiologyresearch.org
We report secondary cutaneous infections in the mouse papillomavirus (MmuPV1)/mouse
model. Our previous study demonstrated that cutaneous MmuPV1 infection could spread to …

The mouse papillomavirus infection model

J Hu, NM Cladel, LR Budgeon, KK Balogh… - Viruses, 2017 - mdpi.com
The mouse papillomavirus (MmuPV1) was first reported in 2011 and has since become a
powerful research tool. Through collective efforts from different groups, significant progress …

[HTML][HTML] Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue

NM Cladel, LR Budgeon, KK Balogh, TK Cooper, J Hu… - Virology, 2016 - Elsevier
In 2010, a new mouse papillomavirus, MmuPV1, was discovered in a colony of NMRI-Foxn1
nu/Foxn1 nu athymic mice in India. This finding was significant because it was the first …

Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1)

A Uberoi, S Yoshida, PF Lambert - Journal of virological methods, 2018 - Elsevier
Preclinical model systems to study multiple features of the papillomavirus life cycle are
extremely valuable tools to aid our understanding of Human Papillomavirus (HPV) biology …