MET and its ligand HGF are involved in many biological processes, both physiological and
pathological, making this signaling pathway an attractive therapeutic target in oncology …

The hepatocyte growth factor/mesenchymal-epithelial transition factor (HGF/c-MET) receptor
tyrosine kinase (RTK) pathway plays a pleotropic role in cell proliferation, migration …

MET is a tyrosine kinase receptor that, upon binding of its natural ligand, the hepatocyte
growth factor (HGF), is phosphorylated and subsequently activates different signalling …

The HGF/MET signaling pathway is critical in mediating a wide range of normal
physiological functions including embryological development, wound healing, and tissue …

The receptor tyrosine kinase c-MET and its ligand, hepatocyte growth factor (HGF), regulate
multiple cellular processes that stimulate cell proliferation, invasion and angiogenesis. This …

Introduction: Under normal conditions, hepatocyte growth factor (HGF)-induced activation of
its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand …

Under normal conditions, hepatocyte growth factor (HGF)-induced Met tyrosine kinase (TK)
activation is tightly regulated by paracrine ligand delivery, ligand activation at the target cell …

The MET receptor tyrosine kinase and its ligand hepatocyte growth factor (HGF) have been
implicated in transformation of a variety of malignancies. Chronic or dysregulated activation …

This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …

The c‐MET receptor tyrosine kinase is the receptor for hepatocyte growth factor. Recently,
activation of the c‐MET/hepatocyte growth factor signaling pathway was associated with …