Epigenetic signatures of cigarette smoking
Background—DNA methylation leaves a long-term signature of smoking exposure and is
one potential mechanism by which tobacco exposure predisposes to adverse health …
one potential mechanism by which tobacco exposure predisposes to adverse health …
Smoking and blood DNA methylation: an epigenome-wide association study and assessment of reversibility
PA Dugué, CH Jung, JE Joo, X Wang, EM Wong… - Epigenetics, 2020 - Taylor & Francis
We conducted a genome-wide association study of blood DNA methylation and smoking,
attempted replication of previously discovered associations, and assessed the reversibility of …
attempted replication of previously discovered associations, and assessed the reversibility of …
Epigenetic signatures of starting and stopping smoking
Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs
J van Dongen, G Willemsen, EJC de Geus… - Elife, 2023 - elifesciences.org
Background: Smoking-associated DNA methylation levels identified through epigenome-
wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms …
wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms …
The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers
R Wilson, S Wahl, L Pfeiffer, CK Ward-Caviness… - BMC genomics, 2017 - Springer
Background The evidence for epigenome-wide associations between smoking and DNA
methylation continues to grow through cross-sectional studies. However, few large-scale …
methylation continues to grow through cross-sectional studies. However, few large-scale …
Tobacco smoking leads to extensive genome-wide changes in DNA methylation
S Zeilinger, B Kühnel, N Klopp, H Baurecht… - PloS one, 2013 - journals.plos.org
Environmental factors such as tobacco smoking may have long-lasting effects on DNA
methylation patterns, which might lead to changes in gene expression and in a broader …
methylation patterns, which might lead to changes in gene expression and in a broader …
Self-reported smoking, serum cotinine, and blood DNA methylation
Y Zhang, I Florath, KU Saum, H Brenner - Environmental research, 2016 - Elsevier
Background Epigenome-wide profiling of DNA methylation pattern with respect to tobacco
smoking has given rise to a new measure of smoking exposure. We investigated the …
smoking has given rise to a new measure of smoking exposure. We investigated the …
DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies
X Gao, M Jia, Y Zhang, LP Breitling, H Brenner - Clinical epigenetics, 2015 - Springer
Active smoking is a major preventable public health problem and an established critical
factor for epigenetic modification. In this systematic review, we identified 17 studies …
factor for epigenetic modification. In this systematic review, we identified 17 studies …
Cigarette smoking and DNA methylation
KWK Lee, Z Pausova - Frontiers in genetics, 2013 - frontiersin.org
DNA methylation is the most studied epigenetic modification, capable of controlling gene
expression in the contexts of normal traits or diseases. It is highly dynamic during early …
expression in the contexts of normal traits or diseases. It is highly dynamic during early …
Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans
Cigarette smoking is an environmental risk factor for many chronic diseases, and disease
risk can often be managed by smoking control. Smoking can induce cellular and molecular …
risk can often be managed by smoking control. Smoking can induce cellular and molecular …