Advances in drug development for hepatocellular carcinoma: clinical trials and potential therapeutic targets

XY Luo, KM Wu, XX He - Journal of Experimental & Clinical Cancer …, 2021 - Springer
Although hepatocellular carcinoma (HCC) is one of the deadliest health burdens worldwide,
few drugs are available for its clinical treatment. However, in recent years, major …

[HTML][HTML] Current and future treatments for hepatocellular carcinoma

A Schlachterman, WW Craft Jr… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) represents a unique challenge for physicians and patients.
There is no definitively curative treatment. Rather, many treatment and management …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

Emerging therapies for hepatocellular carcinoma (HCC)

E Chakraborty, D Sarkar - Cancers, 2022 - mdpi.com
Simple Summary Primary liver cancer, also known as Hepatocellular carcinoma (HCC), is
considered to be a major global health challenge. Due to delays in diagnosis at early …

Hepatocellular carcinoma: etiology and current and future drugs

A Jindal, A Thadi, K Shailubhai - Journal of clinical and experimental …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is swiftly increasing in prevalence globally with a high
mortality rate. The progression of HCC in patients is induced with advanced fibrosis, mainly …

Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now?

RS Finn - Clinical Cancer Research, 2010 - AACR
Hepatocellular carcinoma (HCC), once considered an orphan disease in the West, has
become a global health concern. It is the third leading cause of cancer death worldwide, and …

Targeted therapy for hepatocellular carcinoma: Challenges and opportunities

S Chen, Q Cao, W Wen, H Wang - Cancer letters, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, which
ranks as the sixth of cancer-related death. Despite the emergence of targeted therapy …

[HTML][HTML] Targeted and immune therapies for hepatocellular carcinoma: predictions for 2019 and beyond

M Kudo - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
Systemic therapy for hepatocellular carcinoma (HCC) has markedly advanced since the
survival benefit of a molecular targeted agent, sorafenib, were demonstrated in the SHARP …

Improved chemotherapy for hepatocellular carcinoma

H Cao, H Phan, LX Yang - Anticancer research, 2012 - ar.iiarjournals.org
Hepatocellular carcinoma (HCC) is the fifth most common cancer and it is the third leading
cause of cancer-related deaths worldwide. Once diagnosed with the disease, only 30-40 …

Hepatocellular carcinoma: molecular pathogenesis and therapeutic advances

B Cucarull, A Tutusaus, P Rider, T Hernáez-Alsina… - Cancers, 2022 - mdpi.com
Simple Summary Patients with unresectable hepatocellular carcinoma (HCC), the most
common primary tumor of the liver, have poor prognosis and are increasing worldwide. The …