Loneliness and social isolation, or a lack of social contact with others, are serious public
health risks, especially in older adults. A National Academies of Sciences, Engineering, and …

We greatly appreciate the comment on our findings. 1 It is true that the associations of
loneliness and frailty with increased dementia risk raise important questions that merit …

Background and Objectives Epidemiologic evidence has shown that social isolation, a low
frequency of social contact with others, is associated with the risk of dementia and late-life …

Background and Objectives To investigate the independent associations of social isolation
and loneliness with incident dementia and to explore the potential neurobiological …

People experience loneliness when their desired social experience does not match their
perceived social reality. New research shows that social relationships are important for …

Background: Social isolation has been suggested to increase the risk to develop cognitive
decline. However, our knowledge on causality and neurobiological underpinnings is still …

Social isolation has become our constant companion in recent months. The quantitatively
minded may wonder how, beyond economic benchmarks like unemployment rates, we …

Background Social health markers have been linked to the development of dementia. We
hypothesize that social health affects brain structure and consequently influences cognitive …

Objective: Social isolation and loneliness are associated with poor health (immunity,
inflammation, etc.) in ageing. The purpose of this scoping review was to investigate the link …

Advances in molecular genetics and neuroimaging now support novel integrative studies of
complex behavioral traits and brain disease. 1 These phenomena connect multiple …