Cartilage diseases

Y Krishnan, AJ Grodzinsky - Matrix Biology, 2018 - Elsevier
Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human
body including bearing loads in articular joints and intervertebral discs, providing joint …

From osteoarthritis treatments to future regenerative therapies for cartilage

J Clouet, C Vinatier, C Merceron, M Pot-vaucel… - Drug discovery today, 2009 - Elsevier
Osteoarthritis (OA) is associated with cartilage degeneration and an accompanying
inflammatory syndrome of the synovium in addition to alteration of the subchondral bone …

[HTML][HTML] An up to date on clinical prospects and management of osteoarthritis

M Maqbool, G Fekadu, X Jiang, F Bekele… - Annals of Medicine and …, 2021 - Elsevier
The rising prevalence of osteoarthritis (OA) in the general population has necessitated the
development of novel treatment options. It is critical to recognize the joint as a separate …

Cartilage biology, pathology, and repair

D Umlauf, S Frank, T Pap, J Bertrand - Cellular and molecular life sciences, 2010 - Springer
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most
prominent type of arthritis encountered in all countries. Although great efforts have been …

Update on the biology of the chondrocyte and new approaches to treating cartilage diseases

MB Goldring - Best practice & research Clinical rheumatology, 2006 - Elsevier
Osteoarthritis (OA) is a joint disease that involves degeneration of articular cartilage, limited
intraarticular inflammation manifested by synovitis and changes in the subchondral bone …

[HTML][HTML] Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments

C Vinatier, J Guicheux - Annals of physical and rehabilitation medicine, 2016 - Elsevier
Articular cartilage is a non-vascularized and poorly cellularized connective tissue that is
frequently damaged as a result of trauma and degenerative joint diseases such as …

Cartilage homeostasis in health and rheumatic diseases

MB Goldring, KB Marcu - Arthritis research & therapy, 2009 - Springer
As the cellular component of articular cartilage, chondrocytes are responsible for
maintaining in a low-turnover state the unique composition and organization of the matrix …

Rethinking articular cartilage regeneration based on a 250-year-old statement

J Malda, J Groll, PR van Weeren - Nature Reviews Rheumatology, 2019 - nature.com
Cartilage has a limited healing capacity; however, studies into the basic biological
characteristics, formation and structural maintenance of the cartilage collagen network are …

Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies

S Muthu, JV Korpershoek, EJ Novais… - Nature Reviews …, 2023 - nature.com
Osteoarthritis (OA) is a disabling condition that affects billions of people worldwide and
places a considerable burden on patients and on society owing to its prevalence and …

Cartilage in normal and osteoarthritis conditions

J Martel-Pelletier, C Boileau, JP Pelletier… - Best practice & research …, 2008 - Elsevier
The preservation of articular cartilage depends on keeping the cartilage architecture intact.
Cartilage strength and function depend on both the properties of the tissue and on their …