Precision oncology in metastatic colorectal cancer—from biology to medicine
Remarkable progress has been made in the development of biomarker-driven targeted
therapies for patients with multiple cancer types, including melanoma, breast and lung …
therapies for patients with multiple cancer types, including melanoma, breast and lung …
The evolving biomarker landscape for treatment selection in metastatic colorectal cancer
The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to
important improvements in patient outcomes. However, it is still necessary to increase …
important improvements in patient outcomes. However, it is still necessary to increase …
Precision medicine for metastatic colorectal cancer: an evolving era
I Guler, G Askan, J Klostergaard… - Expert review of …, 2019 - Taylor & Francis
Introduction: Metastatic colorectal cancer (CRC) remains a dilemma for cancer researchers
with an increasing incidence in the younger patient population. Until the last decade, limited …
with an increasing incidence in the younger patient population. Until the last decade, limited …
Recent developments in the treatment of metastatic colorectal cancer
Over the past decade there have been significant advances in the molecular
characterization of colorectal cancer (CRC) that are driving treatment decisions. Expanded …
characterization of colorectal cancer (CRC) that are driving treatment decisions. Expanded …
[HTML][HTML] Targeted therapy in metastatic colorectal cancer–an example of personalised medicine in action
V Heinemann, JY Douillard, M Ducreux… - Cancer treatment …, 2013 - Elsevier
In metastatic colorectal cancer (mCRC), an improved understanding of the underlying
pathology and molecular biology has successfully merged with advances in diagnostic …
pathology and molecular biology has successfully merged with advances in diagnostic …
Molecular markers in the treatment of metastatic colorectal cancer
Although significant progress has been made in colorectal cancer (CRC) treatment within
the last decade with the approval of multiple new agents, the prognosis for patients with …
the last decade with the approval of multiple new agents, the prognosis for patients with …
Targeting EGFR pathway in metastatic colorectal cancer-tumour heterogeniety and convergent evolution
Despite significant progress in management of metastatic colorectal cancer (mCRC)
pertaining to better screening procedures and amelioration of the therapeutic …
pertaining to better screening procedures and amelioration of the therapeutic …
Clinical management of metastatic colorectal cancer in the era of precision medicine
F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …
Metastatic colorectal cancer in the era of personalized medicine: a more tailored approach to systemic therapy
IS Yu, WY Cheung - Canadian Journal of Gastroenterology and …, 2018 - Wiley Online Library
Colorectal cancer is the second most common malignancy diagnosed in Canada. Despite
declining incidence and mortality rates in recent years, there is still a significant number of …
declining incidence and mortality rates in recent years, there is still a significant number of …
Molecular targets for the treatment of metastatic colorectal cancer
Over the past years, colorectal cancer (CRC) was subtyped according to its molecular and
genetic characteristics, allowing the development of therapeutic strategies, based on …
genetic characteristics, allowing the development of therapeutic strategies, based on …