[HTML][HTML] Treatment of liver fibrosis: Past, current, and future

CY Zhang, S Liu, M Yang - World Journal of Hepatology, 2023 - ncbi.nlm.nih.gov
Liver fibrosis accompanies the progression of chronic liver diseases independent of
etiologies, such as hepatitis viral infection, alcohol consumption, and metabolic-associated …

[HTML][HTML] Antihepatic fibrosis drugs in clinical trials

YC Guo, LG Lu - Journal of Clinical and Translational Hepatology, 2020 - ncbi.nlm.nih.gov
Liver fibrosis is not an independent disease. It refers to the abnormal proliferation of
connective tissues in the liver caused by various pathogenic factors. Thus far, liver fibrosis …

[HTML][HTML] Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts

R Weiskirchen, S Weiskirchen, F Tacke - F1000Research, 2018 - ncbi.nlm.nih.gov
Hepatic fibrosis is characterized by the formation and deposition of excess fibrous
connective tissue, leading to progressive architectural tissue remodeling. Irrespective of the …

Pathophysiology and treatment options for hepatic fibrosis: can it be completely cured?

A Khanam, PG Saleeb, S Kottilil - Cells, 2021 - mdpi.com
Hepatic fibrosis is a dynamic process that occurs as a wound healing response against liver
injury. During fibrosis, crosstalk between parenchymal and non-parenchymal cells …

Hepatic fibrosis: emerging therapies

SL Friedman - Digestive Diseases, 2015 - karger.com
There has been tremendous progress made in understanding the pathogenesis of hepatic
fibrosis, which has created new opportunities for the treatment of this condition. Clinical …

[PDF][PDF] Liver fibrosis: a clinical update

LC Shipley, PD Axley, AK Singal - Hepatology, 2019 - emjreviews.com
Liver fibrosis is a disease that affects patients with hepatitis B virus or hepatitis C virus,
harmful alcohol consumption levels, and nonalcoholic fatty liver disease. It is important to …

[HTML][HTML] Current and emerging approaches for hepatic fibrosis treatment

J Li, B Tuo - Gastroenterology research and practice, 2021 - hindawi.com
Liver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and
risk of hepatocellular carcinoma (HCC) which are major health burden worldwide …

Liver fibrosis: the 2017 state of art

G Caviglia, C Rosso, S Fagoonee, GM Saracco… - Panminerva …, 2017 - iris.unito.it
Liver fibrosis is a wound-healing response to a wide spectrum of chronic liver injuries. It is
characterized by loss of hepatocytes and alteration in hepatic architecture following an …

Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches

A Ahmad, R Ahmad - Saudi Journal of Gastroenterology, 2012 - journals.lww.com
Hepatic fibrosis (HF) is a progressive condition with serious clinical complications arising
from abnormal proliferation and amassing of tough fibrous scar tissue. This defiance of …

Liver fibrosis

R Bataller, DA Brenner - The Journal of clinical investigation, 2005 - Am Soc Clin Investig
Liver fibrosis is the excessive accumulation of extracellular matrix proteins including
collagen that occurs in most types of chronic liver diseases. Advanced liver fibrosis results in …