Skin microbiota–host interactions

YE Chen, MA Fischbach, Y Belkaid - Nature, 2018 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …

Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

The skin microbiota: balancing risk and reward

L Flowers, EA Grice - Cell host & microbe, 2020 - cell.com
The skin microbiome is an ecosystem comprised of a multitude of microbial species
interacting with their surroundings, including other microbes and host epithelial and immune …

Dialogue between skin microbiota and immunity

Y Belkaid, JA Segre - Science, 2014 - science.org
Human skin, the body's largest organ, functions as a physical barrier to bar the entry of
foreign pathogens, while concomitantly providing a home to myriad commensals. Over a …

Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

Microbial ecology of the skin in the era of metagenomics and molecular microbiology

GD Hannigan, EA Grice - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
The skin is the primary physical barrier between the body and the external environment and
is also a substrate for the colonization of numerous microbes. Previously, dermatological …

Mechanisms of microbe-immune system dialogue within the skin

N Lunjani, S Ahearn-Ford, FS Dube, C Hlela… - Genes & …, 2021 - nature.com
The prevalence and severity of dermatological conditions such as atopic dermatitis have
increased dramatically during recent decades. Many of the factors associated with an …

The influence of skin microorganisms on cutaneous immunity

Y Belkaid, S Tamoutounour - Nature Reviews Immunology, 2016 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by many microorganisms.
Recent evidence highlights the profound reliance of the skin immune system on its resident …

Microbial guardians of skin health

A Stacy, Y Belkaid - Science, 2019 - science.org
Skin, our largest and outermost organ, faces numerous challenges, including wounds,
infections, inflammatory disorders, and cancer. Fortunately, it does not meet these …

The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming

SL Prescott, DL Larcombe, AC Logan, C West… - World Allergy …, 2017 - Springer
Skin barrier structure and function is essential to human health. Hitherto unrecognized
functions of epidermal keratinocytes show that the skin plays an important role in adapting …