[HTML][HTML] In Search of a Function for the N6-Methyladenosine in Epitranscriptome, Autophagy and Neurodegenerative Diseases

N Suga, Y Ikeda, S Yoshikawa, K Taniguchi… - Neurology …, 2023 - mdpi.com
Changes in epitranscriptome with N6-methyladenine (m6A) modification could be involved
in the development of multiple diseases, which might be a prevalent modification of …

[HTML][HTML] m6A methylation: Critical roles in aging and neurological diseases

Y Fan, X Lv, Z Chen, Y Peng, M Zhang - Frontiers in Molecular …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotic
cells, which participates in the functional regulation of various biological processes. It …

[HTML][HTML] METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events

F Zhao, Y Xu, S Gao, L Qin, Q Austria… - Molecular …, 2021 - Springer
Abstract Background N6-methyladenosine (m 6 A) modification of RNA influences
fundamental aspects of RNA metabolism and m 6 A dysregulation is implicated in various …

[HTML][HTML] Novel insights into the roles of N6-methyladenosine (m6A) modification and autophagy in human diseases

J Liang, J Sun, W Zhang, X Wang, Y Xu… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Autophagy is an evolutionarily conserved cellular degradation and recycling process. It is
important for maintaining vital cellular function and metabolism. Abnormal autophagy activity …

[HTML][HTML] Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases

X Chen, J Wang, M Tahir, F Zhang, Y Ran, Z Liu… - Cell & bioscience, 2021 - Springer
Autophagy is a conserved degradation process crucial to maintaining the primary function of
cellular and organismal metabolism. Impaired autophagy could develop numerous …

[HTML][HTML] Role of N6-methyladenosine modification in central nervous system diseases and related therapeutic agents

J Lv, L Xing, X Zhong, K Li, M Liu, K Du - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract N6-methyladenosine (m6A) is a ubiquitous mRNA modification in eukaryotes. m6A
occurs through the action of methyltransferases, demethylases, and methylation-binding …

Dynamic N6-methyladenosine RNA methylation in brain and diseases

AM Shafik, EG Allen, P Jin - Epigenomics, 2020 - Taylor & Francis
N6-methyladenosine (m6A) is a dynamic RNA modification that regulates various aspects of
RNA metabolism and has been implicated in many biological processes and transitions …

N6-methyladenosine and neurological diseases

N Zhang, C Ding, Y Zuo, Y Peng, L Zuo - Molecular neurobiology, 2022 - Springer
Abstract N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the
adenosine N6 position and is the most common chemical epigenetic modification among …

[HTML][HTML] RNA N6-methyladenosine modifications and its roles in Alzheimer's disease

R Zhang, Y Zhang, F Guo, S Li, H Cui - Frontiers in cellular …, 2022 - frontiersin.org
The importance of epitranscriptomics in regulating gene expression has received
widespread attention. Recently, RNA methylation modifications, particularly N6 …

[HTML][HTML] m6A RNA methylation in brain injury and neurodegenerative disease

J Deng, X Chen, A Chen, X Zheng - Frontiers in Neurology, 2022 - frontiersin.org
N6-methyladenosine (m6A), the most prevalent post-transcriptional RNA modification
throughout the eukaryotic transcriptome, participates in diverse biophysiological processes …