[HTML][HTML] Positive feedback loop of SNAIL-IL-6 mediates myofibroblastic differentiation activity in precancerous oral submucous fibrosis

CY Peng, YW Liao, MY Lu, CM Yang, PL Hsieh, CC Yu - Cancers, 2020 - mdpi.com
Oral submucosal fibrosis (OSF) is a premalignant disorder of the oral cavity, and areca nut
chewing is known to be a major etiological factor that could induce epithelial to …

[HTML][HTML] LINC00084/miR-204/ZEB1 axis mediates myofibroblastic differentiation activity in fibrotic buccal mucosa fibroblasts: therapeutic target for oral submucous …

YH Lee, YW Liao, MY Lu, PL Hsieh, CC Yu - Journal of personalized …, 2021 - mdpi.com
Oral submucosal fibrosis (OSF) is a precancerous condition in the oral cavity and areca nut
consumption has been regarded as one of the etiologic factors implicated in the …

Slug mediates myofibroblastic differentiation to promote fibrogenesis in buccal mucosa

CY Fang, SM Hsia, PL Hsieh, YW Liao… - Journal of Cellular …, 2019 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) has been implicated in fibrogenesis and
carcinogenesis; however, the exact role of EMT‐inducer Slug in the progression of …

Hinokitiol ablates myofibroblast activation in precancerous oral submucous fibrosis by targeting Snail

HW Yang, MY Lu, YW Chiu, YW Liao… - Environmental …, 2018 - Wiley Online Library
Oral submucous fibrosis (OSF) is a precancerous condition with symptoms of limited mouth
opening and areca nut chewing habit has been implicated in its pathogenesis. Hinokitiol, a …

[HTML][HTML] Aberrant SSEA-4 upregulation mediates myofibroblast activity to promote pre-cancerous oral submucous fibrosis

CC Yu, CH Yu, YC Chang - Scientific reports, 2016 - nature.com
Oral submucous fibrosis (OSF), regarded as a precancerous condition, is characterized by
juxta-epithelial inflammatory reaction followed by fibro-elastic change in the lamina properia …

Glabridin inhibits the activation of myofibroblasts in human fibrotic buccal mucosal fibroblasts through TGF‐β/smad signaling

PH Lee, PM Chu, PL Hsieh, HW Yang… - Environmental …, 2018 - Wiley Online Library
Oral submucous fibrosis (OSF) has been recognized as one of the oral potentially malignant
disorders. Areca nut chewing is implicated in this pathological fibrosis, and it causes chronic …

Butylidenephthalide abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis

TR Su, YW Liao, PL Hsieh, LL Tsai… - Environmental …, 2018 - Wiley Online Library
Oral submucous fibrosis (OSF) is a premalignant disorder in the oral cavity, and areca nut
chewing habit has been implicated in the persistent activation of myofibroblasts and the …

[HTML][HTML] Areca nut-induced oral fibrosis–Reassessing the biology of oral submucous fibrosis

M Sharma, SC Sarode, G Sarode… - Journal of Oral …, 2024 - Elsevier
Background Oral submucous fibrosis (OSF) is a pathological condition characterized by
excessive tissue healing resulting from physical, chemical, or mechanical trauma. Notably …

[HTML][HTML] Tanshinone suppresses arecoline-induced epithelial–Mesenchymal transition in oral submucous fibrosis by epigenetically reactivating the p53 pathway

L Zheng, ZJ Guan, WT Pan, TF Du, YJ Zhai… - Oncology …, 2018 - ncbi.nlm.nih.gov
Oral submucous fibrosis (OSF) induced by chewing of the areca nut has been considered to
be a precancerous lesion with a high probability of developing oral squamous cell …

[HTML][HTML] Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous Fibrosis

I Pant, SG Rao, P Kondaiah - Scientific reports, 2016 - nature.com
Oral submucous fibrosis (OSF) is potentially premalignant with progressive and irreversible
extracellular matrix deposition accompanied by epithelial atrophy and like other fibrotic …