Pseudomonas aeruginosa, a Gram‐negative bacterium, is a significant opportunistic
pathogen associated with skin and soft tissue infections, nosocomial pneumonia and sepsis …

Pseudomonas aeruginosa strains associated with cystic fibrosis are often mucoid due to the
copious production of alginate, an exopolysaccharide and virulence factor. Alginate gene …

The conversion to mucoid, exopolysaccharide alginate‐overproducing phenotype in
Pseudomonas aeruginosa during chronic respiratory infections in cystic fibrosis patients …

Overproduction of the exopolysaccharide alginate causes mucoid conversion in
Pseudomonas aeruginosa and is a poor prognosticator in cystic fibrosis. The ECF σ factor …

Conversion from the nonmucoid to the mucoid phenotype is a typical feature of
Pseudomonas aeruginosa strains causing chronic pulmonary infections in cystic fibrosis …

Mucoidy, or overproduction of the exopolysaccharide known as alginate, in Pseudomonas
aeruginosa is a poor prognosticator for lung infections in cystic fibrosis. Mutation of the anti-σ …

Mucoidy in Pseudomonas aeruginosa is a critical virulence factor associated with chronic
respiratory infections in cystic fibrosis. A cluster of three tightly linked genes. algU, mucA and …

MucA sequesters extracytoplasmic function (ECF) σ22 (algT/U encoded) from target
promoters including PalgD for alginate biosynthesis. We have shown that cell wall stress (eg …

Alginate overproduction, or mucoidy, plays an important role in the pathogenesis of P.
aeruginosa lung infection in cystic fibrosis (CF). Mucoid strains with mucA mutations …

The mucoid phenotype is common among strains of Pseudomonas aeruginosa that cause
chronic pulmonary infections in patients with cystic fibrosis and is due to overproduction of …