Colloidal polyelectrolyte complexes from hyaluronic acid: Preparation and biomedical applications

HV Le, D Le Cerf - Small, 2022 - Wiley Online Library
Hyaluronic acid (HA) is a naturally occurring polysaccharide which has been extensively
exploited in biomedical fields owing to its outstanding biocompatibility. Self‐assembly of HA …

Polyelectrolyte complexes of hyaluronic acid and diethylaminoethyl dextran: Formation, stability and hydrophobicity

H Van Le, V Dulong, L Picton, D Le Cerf - Colloids and Surfaces A …, 2021 - Elsevier
Polyelectrolyte complexes (PECs) of hyaluronic acid (HA) and diethylaminoethyl dextran
(DEAE-D), promising for biomedical applications, have been investigated with respect to …

Polyelectrolyte complexes of natural polymers and their biomedical applications

M Ishihara, S Kishimoto, S Nakamura, Y Sato, H Hattori - Polymers, 2019 - mdpi.com
Polyelectrolyte complexes (PECs), composed of natural and biodegradable polymers,(such
as positively charged chitosan or protamine and negatively charged glycosaminoglycans …

Polyelectrolyte complexes via desalting mixtures of hyaluronic acid and chitosan—Physicochemical study and structural analysis

G Lalevée, G Sudre, A Montembault, J Meadows… - Carbohydrate …, 2016 - Elsevier
Polyelectrolyte complexes (PECs) were prepared from Chitosan (CS) and Hyaluronic Acid
(HYA) homogeneous mixtures of aqueous solutions. The method consisted of preparing a …

Polysaccharide-based polyelectrolyte complex systems for biomedical uses

S Alkahtani, MS Hasnain, AK Nayak… - … Made Polysaccharides in …, 2020 - Elsevier
Polyelectrolytes (PEs) instinctively attain a net positive or negative charge when mixed in
water. The PEs effectively coreact in aqueous mediums and could transform into the …

Elaboration of stable and antibody functionalized positively charged colloids by polyelectrolyte complexation between chitosan and hyaluronic acid

RC Polexe, T Delair - Molecules, 2013 - mdpi.com
In this study, we describe the elaboration of multifunctional positively charged polyelectrolyte
complex (PEC) nanoparticles, designed to be stable at physiological salt concentration and …

Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers

A Umerska, KJ Paluch, I Inkielewicz-Stępniak… - International journal of …, 2012 - Elsevier
The aim of this work was to study the formulation of pharmaceutically relevant polyelectrolyte
complex nanoparticles (NPs) composed of hyaluronic acid (HA) and chitosan (CS) …

Stabilization of chitosan/hyaluronan colloidal polyelectrolyte complexes in physiological conditions

D Wu, T Delair - Carbohydrate polymers, 2015 - Elsevier
Polyelectrolyte complexes (PECs) between hyaluronan (HYA) and chitosan were obtained
by the one-shot addition of default amounts of polyanion to an excess of polycation. The …

Versatile and efficient formation of colloids of biopolymer-based polyelectrolyte complexes

C Schatz, A Domard, C Viton, C Pichot… - …, 2004 - ACS Publications
The formation of colloids based on polyelectrolyte complexes (PECs) of biopolymers was
investigated through the complexation between two charged polysaccharides, chitosan as …

Colloidal polyelectrolyte complexes of chitosan and dextran sulfate towards versatile nanocarriers of bioactive molecules

T Delair - European Journal of Pharmaceutics and …, 2011 - Elsevier
Nanomedicine is an emerging field and requires new tools to achieve its goals, such as
nanomaterials capable of performing various functions as bioactive (macro) molecule …