Systemic sclerosis is an autoimmune disease leading to vasculopathy and fibrosis of skin
and internal organs. Despite likely shared pathogenic mechanisms, the patterns of skin and …

Systemic sclerosis (scleroderma, SSc) is a heterogeneous autoimmune connective tissue
disease of unknown etiology. Interstitial lung disease (ILD) is a frequent complication, and a …

Systemic sclerosis (SSc) is a complex, multiorgan, autoimmune disease. Lung fibrosis
occurs in∼ 80% of patients with SSc; 25% to 30% develop progressive interstitial lung …

Systemic sclerosis (SSc), or scleroderma, is a rare, complex, systemic autoimmune disease
of unknown aetiology, characterized by high morbidity and mortality often resulting from …

Objective Systemic sclerosis (SSc)–related interstitial lung disease (ILD) is one of the
leading causes of mortality. We undertook this study to analyze the gene expression of lung …

The natural history of interstitial lung disease in patients with systemic sclerosis is highly
variable. Historical observational studies have demonstrated that the greatest decline in …

Fibrosis of the lung, a common complication of systemic sclerosis (SSc) and the hallmark of
idiopathic pulmonary fibrosis (IPF), is associated with substantial mortality and has no …

Objective To investigate the relationship between Krebs von den Lungen 6 (KL‐6) and CCL
18 levels and the severity and progression of systemic sclerosis (SS c)–related interstitial …

Fibrosis of the pulmonary parenchyma is a frequent and serious complication of
scleroderma (systemic sclerosis, SSc), resulting in significant morbidity and mortality. During …

Rationale: Previous studies have suggested that interstitial lung disease (ILD) progresses
most rapidly early in the course of systemic sclerosis–associated (SSc)-ILD, and that SSc …