Pressurized metered dose inhaler is the most common inhaled dosage form, ideally suited
for delivering the highly potent compounds that medicinal chemists typically discover for …

Objectives The formulation of multi-drug pressurised metered dose inhalers (pMDIs) opens
up exciting therapeutic opportunities for the treatment of asthma and chronic obstructive …

Inhaled therapeutic aerosols continue to be an important treatment for asthma and
pulmonary diseases. A variety of dosage forms are employed for different indications and …

Technologies for long-term delivery of aerosol medications in asthma and chronic
obstructive pulmonary disease have improved over the past 2 decades with advancements …

Purpose: A new approach to delivering high doses of dry powder medicaments to the lung is
presented. The Orbital® dry powder device is designed to deliver high doses of drugs to the …

Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

Introduction: Airway inflammation and remodelling in asthma occur in the large airways and
also in the small airways. The small airways are those< 2 mm in diameter and are significant …

Inhaled medicines are designed mainly to provide safe and efficacious treatment of
respiratory diseases, offering the potential advantages of targeted drug delivery such as …

Background Bronchodilator medications are central to the symptomatic management of
chronic obstructive pulmonary disease (COPD). Metered-dose inhalers (MDIs) are the most …

In recent years, the inhalation route has gained importance for the treatment of both
pulmonary and extrapulmonary diseases. Delivery of drugs or bioactive molecules through …