Bioactive glass nanoparticles inhibit osteoclast differentiation and osteoporotic bone loss by activating lncRNA NRON expression in the extracellular vesicles derived …

Z Yang, X Liu, F Zhao, M Yao, Z Lin, Z Yang, C Liu… - Biomaterials, 2022 - Elsevier
Bioactive glass nanoparticles (BGN) have attracted increasing attention for their use in bone
tissue repair owing to their special osteogenic activity; however, the underlying molecular …

Human mesenchymal stem cells differentiate into an osteogenic lineage in presence of strontium containing bioactive glass nanoparticles

P Naruphontjirakul, O Tsigkou, S Li, AE Porter… - Acta biomaterialia, 2019 - Elsevier
While bioactive glass and ions released during its dissolution are known to stimulate
osteoblast cells, the effect bioactive glass has on human stem cells is not clear. Here, we …

Monodispersed bioactive glass nanoclusters with ultralarge pores and intrinsic exceptionally high miRNA loading for efficiently enhancing bone regeneration

Y Xue, Y Guo, M Yu, M Wang, PX Ma… - Advanced Healthcare …, 2017 - Wiley Online Library
Bioactive glass nanoparticles (BGNs) have attracted much attention in drug delivery and
bone tissue regeneration, due to the advantages including biodegradation, high bone …

In vitro response of human osteoblasts to multi-step sol–gel derived bioactive glass nanoparticles for bone tissue engineering

JP Fan, P Kalia, L Di Silvio, J Huang - Materials Science and Engineering …, 2014 - Elsevier
A multi-step sol–gel process was employed to synthesize bioactive glass (BG)
nanoparticles. Transmission electron microscopy (TEM) revealed that the BG nanoparticles …

In vitro osteogenesis by intracellular uptake of strontium containing bioactive glass nanoparticles

P Naruphontjirakul, AE Porter, JR Jones - Acta Biomaterialia, 2018 - Elsevier
Monodispersed strontium containing bioactive glass nanoparticles (Sr-BGNPs) with two
compositions were synthesised, through a modified sol-gel Stöber process, wherein silica …

Multifunctional Zn and Ag co-doped bioactive glass nanoparticles for bone therapeutic and regeneration

P Naruphontjirakul, P Kanchanadumkerng… - Scientific Reports, 2023 - nature.com
Bone cancer has traditionally been treated using surgery, radiotherapy, and/or
chemotherapy. The nonspecific distribution of chemotherapy and implantable infections are …

Novel strontium-doped bioactive glass nanoparticles enhance proliferation and osteogenic differentiation of human bone marrow stromal cells

LA Strobel, N Hild, D Mohn, WJ Stark, A Hoppe… - Journal of nanoparticle …, 2013 - Springer
The present study investigates a new family of bioactive glass nanoparticles with and
without Sr-doping focusing on the influence of the nanoparticles on human bone marrow …

Gadolinium-doped bioglass scaffolds promote osteogenic differentiation of hBMSC via the Akt/GSK3β pathway and facilitate bone repair in vivo

DY Zhu, B Lu, JH Yin, QF Ke, H Xu… - International Journal …, 2019 - Taylor & Francis
Background Biomaterial-induced osteogenesis is mainly related to hierarchically porous
structures and bioactive components. Rare earth elements are well known to promote …

Strontium-doped bioactive glass nanoparticles in osteogenic commitment

ÁJ Leite, AI Gonçalves, MT Rodrigues… - … applied materials & …, 2018 - ACS Publications
The present work has explored bioactive glass nanoparticles (BGNPs) and developed
strontium-doped nanoparticles (BGNPsSr), envisioning orthopedic strategies compatible …

Effect of manganese, zinc, and copper on the biological and osteogenic properties of mesoporous bioactive glass nanoparticles

F Westhauser, S Wilkesmann, Q Nawaz… - … Research Part A, 2021 - Wiley Online Library
Mesoporous bioactive glass nanoparticles (MBGNs) have demonstrated promising
properties for the local delivery of therapeutically active ions with the aim to improve their …