FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin), a 5-fluorouracil (5-FU)-based
chemotherapy regimen, is one of most common therapeutic regimens for colorectal cancer …

Many lines of evidence demonstrate the associations of colorectal cancer (CRC) with
intestinal microbial dysbiosis. Recent reports have suggested that maintaining the …

Colitis-associated cancer (CAC) is the most serious outcome of inflammatory bowel disease,
which has an alteration of commensal intestinal microbiota. However, the role of intestinal …

Adjuvant 5-fluorouracil (5-FU)-based chemotherapy, including FOLFOX (5-FU, leucovorin,
and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis …

Inflammatory bowel disease (IBD) is an increasing global burden and a predisposing factor
to colorectal cancer. Although a number of treatment options are available, the side effects …

BACKGROUND Emerging evidence has demonstrated that fecal microbiota transplantation
(FMT) has a promising therapeutic effect on mice with experimental colitis and patients with …

Colorectal cancer is one of the most frequently diagnosed cancers worldwide. Gut flora can
modulate the host response to chemotherapeutic drugs. However, the understanding …

Ulcerative colitis (UC) is a chronic non-specific inflammatory disease that occurs in the colon
and rectum. While fecal microbiota transplantation (FMT) is gaining attention as a clinical …

The human gut is home to a large and diverse microbial community, comprising about 1,000
bacterial species. The gut microbiota exists in a symbiotic relationship with its host, playing a …

Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-
fluorouracil (5-Fu) induced mucositis. However, current knowledge of the overall profiles of 5 …