Lipoxidation adducts with peptides and proteins: deleterious modifications or signaling mechanisms?
RM Domingues, P Domingues, T Melo… - Journal of …, 2013 - Elsevier
Protein lipoxidation refers to the modification by electrophilic lipid oxidation products to form
covalent adducts, which for many years has been considered as a deleterious consequence …
covalent adducts, which for many years has been considered as a deleterious consequence …
[HTML][HTML] Protein lipoxidation: detection strategies and challenges
Enzymatic and non-enzymatic lipid metabolism can give rise to reactive species that may
covalently modify cellular or plasma proteins through a process known as lipoxidation …
covalently modify cellular or plasma proteins through a process known as lipoxidation …
Protein modifications by electrophilic lipoxidation products: adduct formation, chemical strategies and tandem mass spectrometry for their detection and identification
YV Vasil'ev, SC Tzeng, L Huang… - Mass Spectrometry …, 2014 - Wiley Online Library
The post‐translational modification of proteins by electrophilic oxylipids is emerging as an
important mechanism that contributes to the complexity of proteomes. Enzymatic and non …
important mechanism that contributes to the complexity of proteomes. Enzymatic and non …
Protein lipoxidation: basic concepts and emerging roles
Á Viedma-Poyatos, P González-Jiménez, O Langlois… - Antioxidants, 2021 - mdpi.com
Protein lipoxidation is a non-enzymatic post-translational modification that consists of the
covalent addition of reactive lipid species to proteins. This occurs under basal conditions but …
covalent addition of reactive lipid species to proteins. This occurs under basal conditions but …
Modification of proteins by reactive lipid oxidation products and biochemical effects of lipoxidation
CM Spickett, AR Pitt - Essays in Biochemistry, 2020 - portlandpress.com
Lipid oxidation results in the formation of many reactive products, such as small aldehydes,
substituted alkenals, and cyclopentenone prostaglandins, which are all able to form covalent …
substituted alkenals, and cyclopentenone prostaglandins, which are all able to form covalent …
Protein adducts generated from products of lipid oxidation: focus on HNE and one
LM Sayre, D Lin, Q Yuan, X Zhu… - Drug metabolism reviews, 2006 - Taylor & Francis
Modification of proteins in conditions of oxidative stress can contribute to protein dysfunction
or tissue damage and disease progression. Bifunctional, most often α, β-unsaturated …
or tissue damage and disease progression. Bifunctional, most often α, β-unsaturated …
[HTML][HTML] Protein oxidation-Formation mechanisms, detection and relevance as biomarkers in human diseases
R Kehm, T Baldensperger, J Raupbach, A Höhn - Redox Biology, 2021 - Elsevier
Generation of reactive oxygen species and related oxidants is an inevitable consequence of
life. Proteins are major targets for oxidation reactions, because of their rapid reaction rates …
life. Proteins are major targets for oxidation reactions, because of their rapid reaction rates …
Oxidative modification of proteins: from damage to catalysis, signaling, and beyond
Significance: The systematic investigation of oxidative modification of proteins by reactive
oxygen species started in 1980. Later, it was shown that reactive nitrogen species could also …
oxygen species started in 1980. Later, it was shown that reactive nitrogen species could also …
[PDF][PDF] Co-oxidation of proteins by oxidizing lipids
KM Schaich - Lipid oxidation pathways, 2008 - researchgate.net
Lipid oxidation is the chemical reaction that most limits shelf life of foods, and it is
increasingly being recognized as a major contributor to oxidative damage in vivo. In foods …
increasingly being recognized as a major contributor to oxidative damage in vivo. In foods …
Oxidative modification of proteins: an emerging mechanism of cell signaling
SB Wall, JY Oh, AR Diers, A Landar - Frontiers in physiology, 2012 - frontiersin.org
There are a wide variety of reactive species which can affect cell function, including reactive
oxygen, nitrogen, and lipid species. Some are formed endogenously through enzymatic or …
oxygen, nitrogen, and lipid species. Some are formed endogenously through enzymatic or …
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